产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
c Myc抗体
目录 :
GTX103436
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
文章摘录数: 8
参考文献 |
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Huang C, Wu D, Lin P, Lee H. Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87. Oncotarget. 2015;6:8698-708 pubmed
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产品信息
目录代码 :
GTX103436
产品名称 :
c Myc抗体
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
26163148,26226629,27894667,25826088,27997180,28914785,29138846
背景 :
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]
更多信息或购买 :
公司信息
GeneTex