产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
STAT3抗体[C3], C末端
目录 :
GTX104616
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类
更多信息或购买 :
文章摘录数: 8
参考文献 |
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Aalinkeel R, Mangum C, Abou Jaoude E, Reynolds J, Liu M, Sundquist K, et al. Galectin-1 Reduces Neuroinflammation via Modulation of Nitric Oxide-Arginase Signaling in HIV-1 Transfected Microglia: a Gold Nanoparticle-Galectin-1 "Nanoplex" a Possible Neurotherapeutic?. J Neuroimmune Pharmacol. 2017;12:133-151 pubmed 出版商
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Chen Y, Lin W, Liao W, Lin Y, Chang J, Tsai F. PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes. Oncotarget. 2015;6:12997-3005 pubmed
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产品信息
目录代码 :
GTX104616
产品名称 :
STAT3抗体[C3], C末端
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
22240483,26079428,27036136,27734898,27875549,28028734,29031202,28232982
背景 :
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
更多信息或购买 :
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GeneTex
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