抗体

PSMC5抗体

GTX105347

100.00μl

299美元

多克隆

兔

nonconjugated

人类, 小鼠, 大鼠

免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片

PSMC5抗体

兔

多克隆

一抗

100.00μl

299美元

IgG

Rabbit Polyclonal antibody to PSMC5 (proteasome (prosome, macropain) 26S subunit, ATPase, 5)

Hu, Ms, Rat

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. [provided by RefSeq]

Recombinant protein encompassing a sequence within the center region of human PSMC5. The exact sequence is proprietary.

0.1M三羟甲基氨基甲烷, 0.1M甘氨酸, 10% 甘油(pH7)。 0.01% 硫柳汞被添加a防腐剂

免疫细胞化学/IF, 免疫组化-P, 免疫印迹

1毫克/毫升

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Sample (30 ug of whole cell lysate) A: A431 (GTX27909) B: Hep G2 (GTX27900) 10% SDS PAGE GTX105347 diluted at 1:1000

PSMC5 antibody detects PSMC5 protein at cytoplasm and nucleus in human hepatocellular carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human hepatocellular carcinoma. PSMC5 antibody (GTX105347) diluted at 1:500.