产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
Bcl-X antibody
目录 :
GTX105661
规格 :
100.00μl
价格 :
299美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 3
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 图 5
Huang Y, Chen Y, Lai Y, Cheng C, Lin T, Su Y, et al. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Int J Mol Med. 2016;37:83-91 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Shoji K, Teishima J, Hayashi T, Ohara S, McKeehan W, Matsubara A. Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells. Oncol Rep. 2014;32:65-70 pubmed 出版商
Moore M, Wang Q, Kennedy C, Silver P. An alternative splicing network links cell-cycle control to apoptosis. Cell. 2010;142:625-36 pubmed 出版商
产品信息
目录号 :
GTX105661
产品名称 :
Bcl-X antibody
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
规格 :
100.00μl
标价 :
299美元
Pubmed号列表 :
20705336
抗体亚型 :
IgG
产品描述 :
Rabbit Polyclonal antibody to Bcl-X (BCL2-like 1)
交叉活性 :
Hu, Ms, Rat
背景 :
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq]
免疫原 :
Recombinant protein encompassing a sequence within the center region of human Bcl-X. The exact sequence is proprietary.
缓冲液 :
0.1M三羟甲基氨基甲烷, 0.1M甘氨酸, 10% 甘油(pH7)。 0.01% 硫柳汞被添加a防腐剂
用途 :
免疫细胞化学/IF, 免疫组化-P, 免疫沉淀, 免疫印迹
浓度 :
0.95毫克/毫升
一般参考 :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
图像Legend_4 :
Bcl-X antibody detects BCL2L1 protein by Western blot analysis. A. 30 µg PC-12 whole cell lysate/extract 12 % SDS-PAGE Bcl-X antibody (GTX105661) dilution: 1:1000
图像Legend_5 :
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using BCL2L1(GTX105661) antibody at 1:500 dilution.
图像Legend_6 :
Immunoprecipitation of Bcl-X protein from HCT-116 whole cell extracts using 5 μg of Bcl-X antibody (GTX105661). Western blot analysis was performed using Bcl-X antibody (GTX105661). EasyBlot anti-Rabbit IgG (GTX221666-01) was used as a secondary reagent.
图像Legend_7 :
Bcl-X antibody detects Bcl-X protein at cytoplasm by immunofluorescent analysis. Sample: SK-N-SH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Bcl-X protein stained by Bcl-X antibody (GTX105661) diluted at 1:200. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000. Blue: Hoechst 33342 staining.
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国