产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
IKB甲抗体
目录 :
GTX110521
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 3
参考文献
Lee H, Jang H, Kim S, Kim H, Lee S, Oh M, et al. Protective Effect of Eupatilin Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice. Transplant Proc. 2016;48:1226-33 pubmed 出版商
Previtera M, Sengupta A. Substrate Stiffness Regulates Proinflammatory Mediator Production through TLR4 Activity in Macrophages. PLoS ONE. 2015;10:e0145813 pubmed 出版商
Yang D, Chang Y, Lin H, Chen Y, Hsu S, Lin J. Inhibitory effect of litchi (Litchi chinensis Sonn.) flower on lipopolysaccharide-induced expression of proinflammatory mediators in RAW264.7 cells through NF-?B, ERK, and JAK2/STAT3 inactivation. J Agric Food Chem. 2014;62:3458-65 pubmed 出版商
产品信息
目录代码 :
GTX110521
产品名称 :
IKB甲抗体
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
24641487,27320593,26710072
背景 :
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM]
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国