产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
AKT1抗体
目录 :
GTX110613
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 3
参考文献
Vazquez Mellado M, Aguilar C, Rocha Zavaleta L. Erythropoietin protects neuroblastoma cells against etoposide and vincristine by activating ERK and AKT pathways but has no effect in kidney cells. Life Sci. 2015;137:142-9 pubmed 出版商
Lee K, Lo H, Tang W, Hsiao H, Yang P. A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine. Sci Rep. 2014;4:6394 pubmed 出版商
Chen Y, Cheng Y, Hung A, Wu Y, Hou M, Tyan Y, et al. The synthetic flavonoid WYC02-9 inhibits cervical cancer cell migration/invasion and angiogenesis via MAPK14 signaling. Gynecol Oncol. 2013;131:734-43 pubmed 出版商
产品信息
目录代码 :
GTX110613
产品名称 :
AKT1抗体
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
24145114,25227736,26232556
背景 :
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国