产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
组蛋白H3K27me3(三甲基化Lys27)抗体
目录 :
GTX121184
规格 :
100.00μl
价格 :
299美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
抗原修饰 :
methylated
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 3
出版应用/物种/样品/稀释参考文献
  • 染色质免疫沉淀 ; 人类; 1-2 ugs
  • 免疫印迹; 人类; 1:1000
Perrigue P, Silva M, Warden C, Feng N, Reid M, Mota D, et al. The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines. Mol Cancer Res. 2015;13:636-50 pubmed 出版商
Liu T, Lo H, Wei L, Hsiao H, Yang P. S-Adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells. Anticancer Drugs. 2015;26:139-47 pubmed 出版商
Jiang X, Yan J, West A, Perry C, Malysheva O, Devapatla S, et al. Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans. FASEB J. 2012;26:3563-74 pubmed 出版商
产品信息
目录号 :
GTX121184
产品名称 :
组蛋白H3K27me3(三甲基化Lys27)抗体
宿主物种 :
兔
克隆性 :
多克隆
抗原修饰 :
Methylated
产品类型 :
一抗
规格 :
100.00μl
标价 :
299美元
Pubmed号列表 :
22549509,25203626
抗体亚型 :
IgG
产品描述 :
Rabbit Polyclonal antibody to Histone H3 (tri-Methyl K27) (histone cluster 1, H3a)
交叉活性 :
Hu, Ms
背景 :
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq]
缓冲液 :
1XPBS, 1% BSA, 20% 甘油(pH7)。 0.01% 硫柳汞被添加a防腐剂
用途 :
免疫细胞化学/IF, 免疫组化-P, 免疫印迹
浓度 :
0.5毫克/毫升
一般参考 :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
图像Legend_4 :
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed A431, using Histone H3 (tri-Methyl K27)(GTX121184) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.
图像Legend_5 :
Immunohistochemical analysis of paraffin-embedded Hela xenograft, using Histon H3 (tri-Methyl K27)(GTX121184) antibody at 1:500 dilution.
图像Legend_6 :
Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 D: THP-1 7.5% SDS PAGE GTX121184 diluted at 1:500
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国