产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
AKT抗体[N3C2], 内部
目录 :
GTX121937
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:150
  • 免疫印迹; 小鼠; 1:1500; 图 4b,4c
Wang X, Chen H, Tian R, Zhang Y, Drutskaya M, Wang C, et al. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. 2017;8:14091 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Tomei P, Masola V, Granata S, Bellin G, Carratu P, Ficial M, et al. Everolimus-induced epithelial to mesenchymal transition (EMT) in bronchial/pulmonary cells: when the dosage does matter in transplantation. J Nephrol. 2016;29:881-891 pubmed
Chen S, Kuo T, Liao Y, Lin M, Tien Y, Huang M. Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway. Oncogene. 2018;37:6041-6053 pubmed 出版商
Wu P, You Y, Liu Y, Hou C, Wu C, Wen K, et al. Sesamol Inhibited Melanogenesis by Regulating Melanin-Related Signal Transduction in B16F10 Cells. Int J Mol Sci. 2018;19: pubmed 出版商
Chang H, Lu C, Chiang J, Tsai F, Juan Y, Tsao J, et al. Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling. Int J Oncol. 2018;: pubmed 出版商
Chen P, Lee W, Ling H, Cheng C, Chen K, Lin C. Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells. J Cell Physiol. 2018;233:4972-4980 pubmed 出版商
Viedma Rodríguez R, Martínez Hernández M, Flores López L, Baiza Gutman L. Epsilon-aminocaproic acid prevents high glucose and insulin induced-invasiveness in MDA-MB-231 breast cancer cells, modulating the plasminogen activator system. Mol Cell Biochem. 2018;437:65-80 pubmed 出版商
Yeh C, Chen C, Leu Y, Lin M, Chiu M, Wang S. The effects of artocarpin on wound healing: in vitro and in vivo studies. Sci Rep. 2017;7:15599 pubmed 出版商
Ni Y, Hsieh C, Kim S, Wang J, Su C, Yao C, et al. A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres. Apoptosis. 2017;22:1235-1245 pubmed 出版商
Liu J, Cao L, Feng Y, Li Y, Li T. MiR-338-3p inhibits TNF-α-induced lipogenesis in human sebocytes. Biotechnol Lett. 2017;39:1343-1349 pubmed 出版商
Chen X, Zhao X, Cai H, Sun H, Hu Y, Huang X, et al. The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways. Redox Biol. 2017;12:987-1003 pubmed 出版商
Wang H, Wang Y, Wu D, Hung C, Chen C, Lee H. Targeting insulin-like growth factor-binding protein-3 by microRNA-125b promotes tumor invasion and poor outcomes in non-small-cell lung cancer. Tumour Biol. 2017;39:1010428317694316 pubmed 出版商
Wang L, Chiou S, Chai C, Hsi E, Chiang C, Huang S, et al. Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer. Oncogene. 2017;36:4405-4414 pubmed 出版商
Chao W, Deng J, Li P, Liang Y, Huang G. 3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways. Molecules. 2017;22: pubmed 出版商
Kuo Y, Chen C, Wu P, Wu C, Sung P, Lin C, et al. N-(4-methoxyphenyl) caffeamide-induced melanogenesis inhibition mechanisms. BMC Complement Altern Med. 2017;17:71 pubmed 出版商
Chen P, Shen W, Shih C, Ho K, Cheng C, Lin C, et al. The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity. Neuropharmacology. 2017;116:300-314 pubmed 出版商
Hsieh C, Lee L, Leong W, Yang T, Yao C, Fang K. A triazole derivative elicits autophagic clearance of polyglutamine aggregation in neuronal cells. Drug Des Devel Ther. 2016;10:2947-2957 pubmed
Chen P, Chang C, Shih C, Cheng C, Lin C, Lee C, et al. The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death. Neuropharmacology. 2016;110:362-375 pubmed 出版商
Chen C, Lin M, Liang C, Wang S. The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages. PLoS ONE. 2016;11:e0158662 pubmed 出版商
Lin C, Lee H, Lee M, Pan S, Ke C, Chiu A, et al. Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma. Int J Mol Sci. 2016;17: pubmed 出版商
Xu Y, Wu D, Zheng W, Yu F, Yang F, Yao Y, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016;7:6146-58 pubmed 出版商
Carpentieri A, Cozzoli E, Scimeca M, Bonanno E, Sardanelli A, Gambacurta A. Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor. Cell Death Dis. 2015;6:e1974 pubmed 出版商
Vallejo Flores G, Torres J, Sandoval Montes C, Arévalo Romero H, Meza I, Camorlinga Ponce M, et al. Helicobacter pylori CagA Suppresses Apoptosis through Activation of AKT in a Nontransformed Epithelial Cell Model of Glandular Acini Formation. Biomed Res Int. 2015;2015:761501 pubmed 出版商
Masola V, Carraro A, Zaza G, Bellin G, Montin U, Violi P, et al. Epithelial to mesenchymal transition in the liver field: the double face of Everolimus in vitro. BMC Gastroenterol. 2015;15:118 pubmed 出版商
Chen C, Lin Y, Chen C, Chao P, Chiou J, Kuo C, et al. Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma. Oncotarget. 2015;6:26946-59 pubmed 出版商
Huang R, Wei Y, Inbaraj B, Chen B. Inhibition of colon cancer cell growth by nanoemulsion carrying gold nanoparticles and lycopene. Int J Nanomedicine. 2015;10:2823-46 pubmed 出版商
Huang Y, Chou W, Hsiung C, Hu L, Chu H, Shen C. FGFR2 regulates Mre11 expression and double-strand break repair via the MEK-ERK-POU1F1 pathway in breast tumorigenesis. Hum Mol Genet. 2015;24:3506-17 pubmed 出版商
Hung C, Chien C, Chiang W, Lin C, Hour T, Chen H, et al. p22phox confers resistance to cisplatin, by blocking its entry into the nucleus. Oncotarget. 2015;6:4110-25 pubmed
Ho W, Chou C, Jeng Y, Lu M, Yang Y, Jou S, et al. GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma. Oncotarget. 2014;5:12247-59 pubmed
Liao W, Ho C, Hou H, Hsu T, Tsai M, Chen K, et al. Heparin co-factor II enhances cell motility and promotes metastasis in non-small cell lung cancer. J Pathol. 2015;235:50-64 pubmed 出版商
Kim J, Kim J, Kim J, Kim S, Chung H, Park C. HOXA10 is associated with temozolomide resistance through regulation of the homologous recombinant DNA repair pathway in glioblastoma cell lines. Genes Cancer. 2014;5:165-174 pubmed
Sun W, Depping R, Jelkmann W. Interleukin-1? promotes hypoxia-induced apoptosis of glioblastoma cells by inhibiting hypoxia-inducible factor-1 mediated adrenomedullin production. Cell Death Dis. 2014;5:e1020 pubmed 出版商
Wu Y, Liu C, Huang M, Lai H, Lee P, Hu R, et al. C1GALT1 enhances proliferation of hepatocellular carcinoma cells via modulating MET glycosylation and dimerization. Cancer Res. 2013;73:5580-90 pubmed 出版商
产品信息
目录代码 :
GTX121937
产品名称 :
AKT抗体[N3C2], 内部
宿主物种 :
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
23832667,25061500,25130770,25788520,25914533,26557697,26561783,26369804,27231905,27487563,27414646,27695292,27986595,28114924,26196246,25686830,25362349,28378642,28368406,28350337,28345588,28499253,28612231,28597147,28741092,24457964,29215705,29142215,29512708,26716417,29642438
背景 :
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
更多信息或购买 :
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
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http://www.genetex.com
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