产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
组蛋白H3抗体
目录 :
GTX122148
规格 :
100.00μl
价格 :
299美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:2000; 图 st13
Hwang W, Jiang J, Yang S, Huang T, Lan H, Teng H, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014;16:268-80 pubmed 出版商
Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, et al. N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication. Nucleic Acids Res. 2019;47:362-374 pubmed 出版商
Lopez Charcas O, Espinosa A, Alfaro A, Herrera Carrillo Z, Ramírez Cordero B, Cortes Reynosa P, et al. The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity. Sci Rep. 2018;8:12995 pubmed 出版商
Hollingworth R, Horniblow R, Forrest C, Stewart G, Grand R. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2017;91: pubmed 出版商
Yang W, Campbell M, Chang P. SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication. PLoS Pathog. 2017;13:e1006216 pubmed 出版商
Li C, Sun L, Pang C. Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis. Sci Rep. 2015;5:9819 pubmed 出版商
Huang Y, Lu Y, Wu J, Chien C, Pi H. The COP9 signalosome converts temporal hormone signaling to spatial restriction on neural competence. PLoS Genet. 2014;10:e1004760 pubmed 出版商
Lee K, Lo H, Tang W, Hsiao H, Yang P. A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine. Sci Rep. 2014;4:6394 pubmed 出版商
Lee Y, Wu W, Ji W, Chen J, Cheng Y, Chiang M, et al. Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy. J Biomed Sci. 2012;19:9 pubmed 出版商
产品信息
目录号 :
GTX122148
产品名称 :
组蛋白H3抗体
宿主物种 :
克隆性 :
多克隆
产品类型 :
一抗
规格 :
100.00μl
标价 :
299美元
Pubmed号列表 :
22283874,25227736,25393278,25909282
抗体亚型 :
IgG
产品描述 :
Rabbit Polyclonal antibody to Histone H3 (histone cluster 1, H3a)
交叉活性 :
Hu, Ms, Dm, Mk, Rice
背景 :
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq]
免疫原 :
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histone H3. The exact sequence is proprietary.
缓冲液 :
1XPBS, 1% BSA, 20% 甘油(pH7)。 0.01% 硫柳汞被添加a防腐剂
用途 :
免疫细胞化学/IF, 免疫组化-P, 免疫沉淀, 免疫印迹, 染色质免疫沉淀法
浓度 :
1毫克/毫升
一般参考 :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
图像Legend_4 :
Cross-linked ChIP was performed with HeLa chromatin extract and 5 μg of either control rabbit IgG or anti-Histone H3 antibody. The precipitated DNA was detected by PCR with primer set targeting to MyoD.
图像Legend_5 :
Histone H3 antibody immunoprecipitates Histone H3 protein in IP experiments. IP Sample: Raji whole cell lysate/extract A : Control with 3 μg of pre-immune rabbit IgG B : Immunoprecipitation of Histone H3 by 3 μg of Histone H3 antibody (GTX122148) 15% SDS-PAGE The immunoprecipitated Histone H3 protein was detected by Histone H3 antibody (GTX122148) diluted at 1 : 1000. EasyBlot anti-rabbit IgG (HRP) (GTX221666-01) was used as a secondary reagent.
图像Legend_6 :
Histone H3 antibody detects HIST1H3A protein by western blot analysis. A. 30 μg A431 whole cell lysate/extract B. 30 μg HeLa whole cell lysate/extract C. 30 μg HepG2 whole cell lysate/extract 15 % SDS-PAGE Histone H3 antibody (GTX122148) dilution: 1:1000
更多信息或购买 :
公司信息
GeneTex
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Irvine, CA92606
support@genetex.com
http://www.genetex.com
886-3-6208988
公司总部: 美国