产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
E钙粘蛋白抗体[N3C2], 内部
目录 :
GTX124178
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类
更多信息或购买 :
文章摘录数: 2
参考文献
Ling H, Kuo C, Lin B, Huang Y, Lin C. Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer. Exp Cell Res. 2017;350:218-225 pubmed 出版商
Lee W, Lee T, Cheng C, Chen K, Chen Y, Lin C. Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-κB-dependent MMP-9 and epithelial-mesenchymal transition expressions. Food Chem Toxicol. 2015;78:33-41 pubmed 出版商
产品信息
目录代码 :
GTX124178
产品名称 :
E钙粘蛋白抗体[N3C2], 内部
宿主物种 :
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
25656647,27914787
背景 :
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq]
更多信息或购买 :
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国