产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
TDG抗体
目录 :
GTX127975
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类
更多信息或购买 :
产品信息
目录代码 :
GTX127975
产品名称 :
TDG抗体
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
背景 :
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq]
更多信息或购买 :
公司信息
GeneTex