产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
AKT(磷酸化Ser473/474/472)抗体
目录 :
GTX128414
规格 :
100.00μl
价格 :
299美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
文章摘录数: 2
| 出版应用/物种/样本/稀释 | 参考文献 |
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产品信息
目录号 :
GTX128414
产品名称 :
AKT(磷酸化Ser473/474/472)抗体
宿主物种 :
兔
克隆性 :
多克隆
抗原修饰 :
磷酸化
产品类型 :
一抗
规格 :
100.00μl
标价 :
299美元
产品描述 :
Rabbit Polyclonal antibody to AKT1+2+3 (phospho Ser473/474/472) (v-akt murine thymoma viral oncogene homolog 1)
交叉活性 :
Hu
背景 :
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
缓冲液 :
1XPBS, 1% BSA, 20% 甘油(pH7)。 0.01% 硫柳汞被添加a防腐剂
用途 :
免疫沉淀, 免疫印迹
浓度 :
0.96毫克/毫升
一般参考 :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
更多信息或购买 :
公司信息
GeneTex