产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
钙联接蛋白抗体
目录 :
GTX13504
规格 :
100.00μl
价格 :
299美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 1
参考文献
Amabile A, Migliara A, Capasso P, Biffi M, Cittaro D, Naldini L, et al. Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing. Cell. 2016;167:219-232.e14 pubmed 出版商
产品信息
目录号 :
GTX13504
产品名称 :
钙联接蛋白抗体
宿主物种 :
克隆性 :
多克隆
产品类型 :
一抗
规格 :
100.00μl
标价 :
299美元
抗体亚型 :
IgG
产品描述 :
兔多抗钙联接蛋白-ER标记
交叉活性 :
Hu, Ms, Cow, Mk, Pig, Rat, Gpig, Hm, Ql, Rb, Shp, Xl
背景 :
Calnexin, also referred to as IP90, p88 and p90, is an ~90 kDa integral membrane protein of the endoplasmic reticulum (ER). Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins. Studies indicate that calnexin associates with the major histocompatability complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes. It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP 78 and GRP 94 and protein disulfide isomerase. Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention. Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids).
免疫原 :
Synthetic peptide: EEDEILNRSPRNRKPRRE conjugated to KLH, corresponding to amino acids 575-593 of Human Calnexin.
缓冲液 :
Preservative: NoneConstituents: Whole Serum
用途 :
流式细胞仪, 免疫细胞化学/IF, 免疫组化, 免疫沉淀, 免疫印迹
浓度 :
1毫克/毫升
一般参考 :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
http://www.genetex.com
886-3-6208988
公司总部: 美国