产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
Fibrillarin antibody [38F3]
目录 :
GTX24566
规格 :
250.00μl
价格 :
289美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
38F3
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 3
出版应用/物种/样品/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:200; 图 2a
Behm M, Wahlstedt H, Widmark A, Eriksson M, Ohman M. Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development. J Cell Sci. 2017;130:745-753 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1 ng/ml; 图 12
Mitrea D, Cika J, Guy C, Ban D, Banerjee P, Stanley C, et al. Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA. elife. 2016;5: pubmed 出版商
Zougman A, Mann M, Wisniewski J. Identification and characterization of a novel ubiquitous nucleolar protein 'NARR' encoded by a gene overlapping the rab34 oncogene. Nucleic Acids Res. 2011;39:7103-13 pubmed 出版商
产品信息
目录号 :
GTX24566
产品名称 :
Fibrillarin antibody [38F3]
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
一抗
规格 :
250.00μl
标价 :
289美元
Pubmed号列表 :
21586586
克隆 :
38F3
抗体亚型 :
IgG1
产品描述 :
Mouse monoclonal [38F3] to Fibrillarin - Nucleolar Marker
交叉活性 :
Hu, Ms, Dm, Rat, Ce, S. pombe, plnt
背景 :
Nop1p / Fibrillarin was originally identified as a nucleolar protein of bakers yeast, Saccharomyces cerevisiae (accession P15646). The Nop1p protein is essential for yeast viability and is localized in the nucleoli. The human homologue of Nop1p is fibrillarin (accession P22087) a component of the nucleolar small nuclear ribonucleoprotein (snRNP) particle. The human fibrillarin gene is located on chromosome 19 (19q13.1). Fibrillarin proteins have been cloned and sequenced from several other species (Mouse, accession P35550, Xenopus accession P22232, C. elegans accession Q22053, and S. pombe accession P35551). The N terminal 80 amino acids contain multiple copies based on the peptide RGG, and the remaining 240 amino acids consist of the fibrillarin domain. A fibrillarin homologue has also been identified in the genome of the archean Methanococcus (accession NC_000909). This protein lacks the RGG rich N-terminal extension but is clearly homologues to the other sequences throughout all of the fibrillarin domain. The structure of this molecule has been determined and shown to consist of 2 extended b-sheets flanked by 4 a-helixes. Patients with the autoimmune disease scleroderma often have strong circulating autoantibodies to a 34kDa protein which was subsequently found to be fibrillarin. Fibrillarin is an excellent marker for the nucleolus.
免疫原 :
Yeast nuclear preparation (S. cerevisiae).Hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates (S. cerevisiae).
缓冲液 :
Preservative: 10mM Sodium Azide; Constituents: Tissue Culture Supernatant
用途 :
免疫细胞化学/IF, 免疫组化, 免疫组化-P, 免疫印迹
浓度 :
tissue culture supernatant
一般参考 :
分成小份儿保存在-20°C或-80°C。 避免反复冻融
图像Legend_4 :
Blot of yeast protein extract stained with the GTX24566 anti-Gibrillarin anitbody, stained a single band at ~34kDa.
更多信息或购买 :
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国