产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
beta连环蛋白抗体[E247]
目录 :
GTX61089
规格 :
100.00μl
价格 :
329美元
克隆性 :
单克隆
宿主 :
兔
共轭标签 :
未共轭
克隆名称 :
E247
反应物种 :
人类, 小鼠, 大鼠, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 4
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 6a
Chang L, Chen T, Chen S, Chen C, Lee C, Wu S, et al. Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation. Oncotarget. 2016;7:67986-68001 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Wang J, Huang F, Kuo M, Wang Z, Tseng T, Chang L, et al. Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers. J Biol Chem. 2014;289:14612-23 pubmed 出版商
Taniguchi K, Moroishi T, de Jong P, Krawczyk M, Grebbin B, Luo H, et al. YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:1643-1648 pubmed 出版商
Shaked H, Hofseth L, Chumanevich A, Chumanevich A, Wang J, Wang Y, et al. Chronic epithelial NF-?B activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci U S A. 2012;109:14007-12 pubmed 出版商
产品信息
目录号 :
GTX61089
产品名称 :
beta连环蛋白抗体[E247]
宿主物种 :
兔
克隆性 :
单克隆
产品类型 :
一抗
规格 :
100.00μl
标价 :
329美元
Pubmed号列表 :
22893683,24713700
克隆 :
E247
抗体亚型 :
IgG
产品描述 :
Rabbit monoclonal antibody [E247] to beta Catenin
交叉活性 :
Hu, Ms, Cow, Mk, Rat, Hm, Shp
背景 :
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
免疫原 :
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human beta Catenin aa 1-100 (N terminal).
缓冲液 :
PBS含50% 甘油, 0.05% BSA和0.01% 叠氮化钠
用途 :
ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
浓度 :
0.029毫克/毫升
一般参考 :
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
http://www.genetex.com
886-3-6208988
公司总部: 美国