产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
DNA连接酶III抗体[1F3]
目录 :
GTX70143
规格 :
100.00μg
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
1F3
反应物种 :
人类, 小鼠, 鸡
应用 :
免疫印迹, 免疫细胞化学, 中和反应, 免疫沉淀
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 16
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 图 4
Ebert F, Weiss A, Bültemeyer M, Hamann I, Hartwig A, Schwerdtle T. Arsenicals affect base excision repair by several mechanisms. Mutat Res. 2011;715:32-41 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Masaoka A, Gassman N, Horton J, Kedar P, Witt K, Hobbs C, et al. Interaction between DNA Polymerase β and BRCA1. PLoS ONE. 2013;8:e66801 pubmed
Horton J, Stefanick D, Gassman N, Williams J, Gabel S, Cuneo M, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013;12:774-85 pubmed 出版商
Prasad R, Williams J, Hou E, Wilson S. Pol β associated complex and base excision repair factors in mouse fibroblasts. Nucleic Acids Res. 2012;40:11571-82 pubmed 出版商
Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, et al. DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Res. 2005;65:4020-30 pubmed
Arakawa H, Bednar T, Wang M, Paul K, Mladenov E, Bencsik-Theilen A, et al. Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells. Nucleic Acids Res. 2012;40:2599-610 pubmed 出版商
Windhofer F, Wu W, Iliakis G. Low levels of DNA ligases III and IV sufficient for effective NHEJ. J Cell Physiol. 2007;213:475-83 pubmed
Singh S, Wu W, Zhang L, Klammer H, Wang M, Iliakis G. Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors. Int J Radiat Oncol Biol Phys. 2011;79:540-8 pubmed 出版商
Dong Z, Tomkinson A. ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha. Nucleic Acids Res. 2006;34:5721-279 pubmed
Horton J, Stefanick D, Prasad R, Gassman N, Kedar P, Wilson S. Base excision repair defects invoke hypersensitivity to PARP inhibition. Mol Cancer Res. 2014;12:1128-39 pubmed 出版商
Paul K, Wang M, Mladenov E, Bencsik-Theilen A, Bednar T, Wu W, et al. DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates. PLoS ONE. 2013;8:e59505 pubmed 出版商
Guo Z, Zheng L, Dai H, Zhou M, Xu H, Shen B. Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Nucleic Acids Res. 2009;37:3431-41 pubmed 出版商
Moscariello M, Iliakis G. Effects of chromatin decondensation on alternative NHEJ. DNA Repair (Amst). 2013;12:972-81 pubmed 出版商
Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton J, et al. DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst). 2010;9:109-19 pubmed 出版商
Okano S, Lan L, Tomkinson A, Yasui A. Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells. Nucleic Acids Res. 2005;33:422-9 pubmed
Leppard J, Dong Z, Mackey Z, Tomkinson A. Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair. Mol Cell Biol. 2003;23:5919-27 pubmed
产品信息
目录号 :
GTX70143
产品名称 :
DNA连接酶III抗体[1F3]
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
一抗
规格 :
100.00μg
标价 :
299美元
Pubmed号列表 :
21782832,15653642,22127868,20006562,19336415,17492771,12897160,15899791,23042675,20950945,17040896,23555685,23826138,23871146,24051048,24770870
克隆 :
1F3
抗体亚型 :
IgG1
产品描述 :
Mouse monoclonal [1F3] to DNA ligase III
交叉活性 :
Hu, Ms, Chk
背景 :
There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair and recombination. DNA Ligase III gene product migrates as a 100kDa (a-form) protein in somatic tissues, is ubiquitously expressed and complexes with XRCC-1 and a 97kDa (§-form) protein that is found in testis. DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
免疫原 :
重组全长人类DNA连接酶III-b
缓冲液 :
磷酸盐缓冲液, pH值7.2, 含无防腐剂
用途 :
中和, 免疫细胞化学/IF, 免疫沉淀, 免疫印迹
浓度 :
1毫克/毫升
一般参考 :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国