产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
Jab1抗体[2A10.8]
目录 :
GTX70203
规格 :
100.00μg
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
2A10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 7
参考文献
Yun J, Tomida A, Andoh T, Tsuruo T. Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5. J Biol Chem. 2004;279:31296-303 pubmed
McCall C, Miliani de Marval P, Chastain P, Jackson S, He Y, Kotake Y, et al. Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development. Mol Cell Biol. 2008;28:5621-33 pubmed 出版商
Gemmill R, Bemis L, Lee J, Sozen M, Baron A, Zeng C, et al. The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway. Oncogene. 2002;21:3507-16 pubmed
Merk M, Zierow S, Leng L, Das R, Du X, Schulte W, et al. The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF). Proc Natl Acad Sci U S A. 2011;108:E577-85 pubmed 出版商
Doronkin S, Djagaeva I, Beckendorf S. CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development. 2002;129:5053-64 pubmed
Jumpertz S, Hennes T, Asare Y, Vervoorts J, Bernhagen J, Schütz A. The β-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells. Cell Signal. 2014;26:2051-9 pubmed 出版商
Korbonits M, Chahal H, Kaltsas G, Jordan S, Urmanova Y, Khalimova Z, et al. Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors. J Clin Endocrinol Metab. 2002;87:2635-43 pubmed
产品信息
目录号 :
GTX70203
产品名称 :
Jab1抗体[2A10.8]
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
一抗
规格 :
100.00μg
标价 :
299美元
Pubmed号列表 :
12397113,12050228,21817065,12032852,15126503,18606781,24882689
克隆 :
2A10
抗体亚型 :
IgG2b
产品描述 :
小鼠单克隆抗体人类Jab1
交叉活性 :
Hu, Ms, Dm, Rat
背景 :
JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the ""Signalosome"", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
免疫原 :
全长小鼠JAB-1基因在大肠杆菌中表达
缓冲液 :
磷酸盐缓冲液, pH值7.4, 含无防腐剂
用途 :
免疫细胞化学/IF, 免疫组化, 免疫沉淀, 免疫印迹
浓度 :
1毫克/毫升
一般参考 :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
图像Legend_4 :
Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE GTX70203 diluted at 1:10000
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国