产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
p53抗体[D01]
目录 :
GTX70214
规格 :
200.00μg
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
D01
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀
, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 5
| 出版应用/物种/样品/稀释 | 参考文献 |
|---|---|
| |
Bensaad K, Tsuruta A, Selak M, Vidal M, Nakano K, Bartrons R, et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell. 2006;126:107-20 pubmed
| |
Luo J, Nikolaev A, Imai S, Chen D, Su F, Shiloh A, et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell. 2001;107:137-48 pubmed
| |
Marchenko N, Zaika A, Moll U. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem. 2000;275:16202-12 pubmed
| |
Vojtesek B, Fisher C, Barnes D, Lane D. Comparison between p53 staining in tissue sections and p53 proteins levels measured by an ELISA technique. Br J Cancer. 1993;67:1254-8 pubmed
|
产品信息
目录号 :
GTX70214
产品名称 :
p53抗体[D01]
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
一抗
规格 :
200.00μg
标价 :
299美元
Pubmed号列表 :
24933654,11672522,16839880,7685617,10821866
克隆 :
D01
抗体亚型 :
IgG2a
产品描述 :
小鼠单克隆抗体人类p53
交叉活性 :
Hu
背景 :
The p53 antibody, clone DO1, specifically recognizes an epitope at the N-terminal end of the human p53 protein between amino acids 20-25. p53 is a tumor suppressor gene that is mutated in a wide variety of sporadic and familial cancers. And p53, as a nuclear protein, mediates cell cycle arrest in response to DNA damage and therefore is important in the maintenance of genomic stability. Recent results indicate an enhanced phosphorylation of p53 by ATM in response to DNA damage on SER15, a mutation which reduces the ability of p53 to arrest cell growth.
免疫原 :
重组人类p53在大肠杆菌中表达
缓冲液 :
PBS
用途 :
ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB, ChIP/Chip
浓度 :
1毫克/毫升
一般参考 :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
GeneTex