| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Sifuentes Dominguez L, Li H, Llano E, Liu Z, Singla A, Patel A, et al. SCGN deficiency results in colitis susceptibility. elife. 2019;8: pubmed 出版商 |
| Koronowski K, Kinouchi K, Welz P, Smith J, Zinna V, Shi J, et al. Defining the Independence of the Liver Circadian Clock. Cell. 2019;177:1448-1462.e14 pubmed 出版商 |
| Taura M, Song E, Ho Y, Iwasaki A. Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat. Proc Natl Acad Sci U S A. 2019;116:2282-2289 pubmed 出版商 |
| Wu M, Chen W, Lu Y, Zhu G, Hao L, Li Y. Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway. Nat Commun. 2017;8:13700 pubmed 出版商 |
| Kong S, Yang Y, Xu Y, Wang Y, Zhang Y, Melo Cardenas J, et al. Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas. Proc Natl Acad Sci U S A. 2016;113:10394-9 pubmed 出版商 |
| Marceau C, Puschnik A, Majzoub K, Ooi Y, Brewer S, Fuchs G, et al. Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens. Nature. 2016;535:159-63 pubmed |
| Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed 出版商 |
| Wang S, Hsu J, Ko C, Chiu N, Kan W, Lai M, et al. Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury. Mol Neurobiol. 2016;53:5912-5927 pubmed 出版商 |
| Goedeke L, Rotllan N, Canfrán Duque A, Aranda J, RamÃrez C, Araldi E, et al. MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels. Nat Med. 2015;21:1280-9 pubmed 出版商 |
| Damiani E, Puebla Osorio N, Gorbea E, Ullrich S. Platelet-Activating Factor Induces Epigenetic Modifications in Human Mast Cells. J Invest Dermatol. 2015;135:3034-3040 pubmed 出版商 |
| Lin A, Beasley F, Olson J, Keller N, Shalwitz R, Hannan T, et al. Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection. PLoS Pathog. 2015;11:e1004818 pubmed 出版商 |
| Aguilar Arnal L, Katada S, Orozco Solis R, Sassone Corsi P. NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1. Nat Struct Mol Biol. 2015;22:312-8 pubmed 出版商 |
| Tontonoz P, Cortez Toledo O, Wroblewski K, Hong C, Lim L, Carranza R, et al. The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice. Mol Cell Biol. 2015;35:1125-38 pubmed 出版商 |
| Lecona E, Narendra V, Reinberg D. USP7 cooperates with SCML2 to regulate the activity of PRC1. Mol Cell Biol. 2015;35:1157-68 pubmed 出版商 |
| Wang J, Xu X, Alontaga A, Chen Y, Liu Y. Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction. Cell Rep. 2014;7:848-58 pubmed 出版商 |
| Nini L, Zhang J, Pandey M, Panicker L, Simonds W. Expression of the G?5/R7-RGS protein complex in pituitary and pancreatic islet cells. Endocrine. 2012;42:214-7 pubmed 出版商 |
| Zhou X, Zhong Y, Molinar Inglis O, Kunkel M, Chen M, Sun T, et al. Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus. Nat Commun. 2020;11:6088 pubmed 出版商 |
| Ngo A, Shurtleff M, Popova K, Kulsuptrakul J, Weissman J, Puschnik A. The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins. elife. 2019;8: pubmed 出版商 |
| Li M, Xu X, Chang C, Zheng L, Shen B, Liu Y. SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts. Nat Commun. 2018;9:2706 pubmed 出版商 |
| Gendarme M, Baumann J, Ignashkova T, Lindemann R, Reiling J. Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1. Mol Biol Cell. 2017;28:3756-3772 pubmed 出版商 |
| Damiani E, Puebla Osorio N, Lege B, Liu J, Neelapu S, Ullrich S. Platelet activating factor-induced expression of p21 is correlated with histone acetylation. Sci Rep. 2017;7:41959 pubmed 出版商 |
| Ho S, Lee Y, Lin W. Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain. J Biol Chem. 2015;290:23026-38 pubmed 出版商 |
| Zhu J, Chen H, Guo X, Qiu X, Hu C, Chamberlin A, et al. Synthesis, molecular modeling, and biological evaluation of novel RAD51 inhibitors. Eur J Med Chem. 2015;96:196-208 pubmed 出版商 |
| Li M, Pokharel S, Wang J, Xu X, Liu Y. RECQ5-dependent SUMOylation of DNA topoisomerase I prevents transcription-associated genome instability. Nat Commun. 2015;6:6720 pubmed 出版商 |
| Ip J, Ko J, Yu V, Chan K, Lam A, Law S, et al. A versatile orthotopic nude mouse model for study of esophageal squamous cell carcinoma. Biomed Res Int. 2015;2015:910715 pubmed 出版商 |
| Patel J, Puck J, Srinivasan R, Brown C, Sunderam U, Kundu K, et al. Nijmegen breakage syndrome detected by newborn screening for T cell receptor excision circles (TRECs). J Clin Immunol. 2015;35:227-33 pubmed 出版商 |
| Chen Y, Chiang H, Litchfield P, Pena M, Juang C, Riley D. Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease. J Biomed Sci. 2014;21:63 pubmed 出版商 |
| Sweet R, Zastre J. HIF1-?-mediated gene expression induced by vitamin B1 deficiency. Int J Vitam Nutr Res. 2013;83:188-97 pubmed 出版商 |
| Haga I, Pechenick Jowers T, Griffiths S, Haas J, Beard P. TRAF2 facilitates vaccinia virus replication by promoting rapid virus entry. J Virol. 2014;88:3664-77 pubmed 出版商 |
| Eckel Mahan K, Patel V, de Mateo S, Orozco Solis R, Ceglia N, Sahar S, et al. Reprogramming of the circadian clock by nutritional challenge. Cell. 2013;155:1464-78 pubmed 出版商 |
| Reiling J, Olive A, Sanyal S, Carette J, Brummelkamp T, Ploegh H, et al. A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens. Nat Cell Biol. 2013;15:1473-85 pubmed 出版商 |
| Thomas R, Roberts D, Kubli D, Lee Y, Quinsay M, Owens J, et al. Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure. Genes Dev. 2013;27:1365-77 pubmed 出版商 |
| Sharma M, Salisbury R, Maurer E, Hussain S, Sulentic C. Gold nanoparticles induce transcriptional activity of NF-κB in a B-lymphocyte cell line. Nanoscale. 2013;5:3747-56 pubmed 出版商 |
| Zhu J, Zhou L, Wu G, Konig H, Lin X, Li G, et al. A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia. EMBO Mol Med. 2013;5:353-65 pubmed 出版商 |
| Wei P, Hsieh Y, Su M, Jiang X, Hsu P, Lo W, et al. Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease. Mol Cell. 2012;48:747-59 pubmed 出版商 |
| Diamant G, Amir Zilberstein L, Yamaguchi Y, Handa H, Dikstein R. DSIF restricts NF-?B signaling by coordinating elongation with mRNA processing of negative feedback genes. Cell Rep. 2012;2:722-31 pubmed 出版商 |
| Ramachandran S, Tran D, Klebba Faerber S, Kardinal C, Whetton A, Tamura T. An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5. RNA. 2011;17:1957-66 pubmed 出版商 |
| Pang T, Clarke M, Ghasem Zadeh A, Lee N, Davey R, MacLean H. A physiological role for androgen actions in the absence of androgen receptor DNA binding activity. Mol Cell Endocrinol. 2012;348:189-97 pubmed 出版商 |
| Kanungo J, Chandrasekharappa S. Menin induces endodermal differentiation in aggregated P19 stem cells by modulating the retinoic acid receptors. Mol Cell Biochem. 2012;359:95-104 pubmed 出版商 |
| Lee S, Chung J, Park M, Joo H, Lee E, Cho E, et al. Apurinic/apyrimidinic endonuclease 1 inhibits protein kinase C-mediated p66shc phosphorylation and vasoconstriction. Cardiovasc Res. 2011;91:502-9 pubmed 出版商 |
| Chen Y, Chen C, Riley D, Chen P. Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR. Cell Cycle. 2011;10:655-63 pubmed |
| Wang Y, Ozawa A, Zaman S, Prasad N, Chandrasekharappa S, Agarwal S, et al. The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization. Cancer Res. 2011;71:371-82 pubmed 出版商 |
| Mancini A, Niemann Seyde S, Pankow R, El Bounkari O, Klebba Färber S, Koch A, et al. THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo. BMC Biol. 2010;8:1 pubmed 出版商 |
| Wang X, Chinnam M, Wang J, Wang Y, Zhang X, Marcon E, et al. Thoc1 deficiency compromises gene expression necessary for normal testis development in the mouse. Mol Cell Biol. 2009;29:2794-803 pubmed 出版商 |
| El Bounkari O, Guria A, Klebba Faerber S, Claussen M, Pieler T, Griffiths J, et al. Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP). FEBS Lett. 2009;583:13-8 pubmed 出版商 |
| Yang J, Li Y, Khoury T, Alrawi S, Goodrich D, Tan D. Relationships of hHpr1/p84/Thoc1 expression to clinicopathologic characteristics and prognosis in non-small cell lung cancer. Ann Clin Lab Sci. 2008;38:105-12 pubmed |
| Byun H, Song J, Kim Y, Piao L, Won M, Park K, et al. Caspase-8 has an essential role in resveratrol-induced apoptosis of rheumatoid fibroblast-like synoviocytes. Rheumatology (Oxford). 2008;47:301-8 pubmed 出版商 |
| Bhandari R, Juluri K, Resnick A, Snyder S. Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis. Proc Natl Acad Sci U S A. 2008;105:2349-53 pubmed 出版商 |
| Ji Y, Prasad N, Novotny E, Kaur S, Elkahloun A, Chen Y, et al. Mouse embryo fibroblasts lacking the tumor suppressor menin show altered expression of extracellular matrix protein genes. Mol Cancer Res. 2007;5:1041-51 pubmed |
| Nini L, Waheed A, Panicker L, Czapiga M, Zhang J, Simonds W. R7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain. BMC Biochem. 2007;8:18 pubmed |
| Li Y, Lin A, Zhang X, Wang Y, Wang X, Goodrich D. Cancer cells and normal cells differ in their requirements for Thoc1. Cancer Res. 2007;67:6657-64 pubmed |
| Birle D, Hedley D. Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors. Cancer Res. 2007;67:1735-43 pubmed |
| Mancini A, El Bounkari O, Norrenbrock A, Scherr M, Schaefer D, Eder M, et al. FMIP controls the adipocyte lineage commitment of C2C12 cells by downmodulation of C/EBP alpha. Oncogene. 2007;26:1020-7 pubmed |
| Wang X, Chang Y, Li Y, Zhang X, Goodrich D. Thoc1/Hpr1/p84 is essential for early embryonic development in the mouse. Mol Cell Biol. 2006;26:4362-7 pubmed |
| Li Y, Wang X, Zhang X, Goodrich D. Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors. Mol Cell Biol. 2005;25:4023-33 pubmed |
| Gasparri F, Sola F, Locatelli G, Muzio M. The death domain protein p84N5, but not the short isoform p84N5s, is cell cycle-regulated and shuttles between the nucleus and the cytoplasm. FEBS Lett. 2004;574:13-9 pubmed |
| Agarwal S, Novotny E, Crabtree J, Weitzman J, Yaniv M, Burns A, et al. Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter. Proc Natl Acad Sci U S A. 2003;100:10770-5 pubmed |
| Jaubert J, Cheng J, Segre J. Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003;130:2767-77 pubmed |
| Sukhodolets K, Hickman A, Agarwal S, Sukhodolets M, Obungu V, Novotny E, et al. The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene. Mol Cell Biol. 2003;23:493-509 pubmed |
| Sunn K, Cock T, Crofts L, Eisman J, Gardiner E. Novel N-terminal variant of human VDR. Mol Endocrinol. 2001;15:1599-609 pubmed |
| Bounpheng M, Melnikova I, Dodds S, Chen H, Copeland N, Gilbert D, et al. Characterization of the mouse JAB1 cDNA and protein. Gene. 2000;242:41-50 pubmed |
