产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
TSG101抗体[4A10]
目录 :
GTX70255
规格 :
100.00μg
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
4A10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 86
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Shibata H, Suzuki H, Kakiuchi T, Inuzuka T, Yoshida H, Mizuno T, et al. Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants. J Biol Chem. 2008;283:9623-32 pubmed 出版商
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Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher E, et al. Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J Cell Biol. 2007;179:485-500 pubmed
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Audhya A, McLeod I, Yates J, Oegema K. MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation. PLoS ONE. 2007;2:e956 pubmed
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Fraile Ramos A, Pelchen Matthews A, Risco C, Rejas M, Emery V, Hassan Walker A, et al. The ESCRT machinery is not required for human cytomegalovirus envelopment. Cell Microbiol. 2007;9:2955-67 pubmed
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De Domenico I, Ward D, Langelier C, Vaughn M, Nemeth E, Sundquist W, et al. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Mol Biol Cell. 2007;18:2569-78 pubmed
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Tampellini D, Magrane J, Takahashi R, Li F, Lin M, Almeida C, et al. Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. J Biol Chem. 2007;282:18895-906 pubmed
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Langelier C, von Schwedler U, Fisher R, De Domenico I, White P, Hill C, et al. Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. J Virol. 2006;80:9465-80 pubmed
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Chertova E, Chertov O, Coren L, Roser J, Trubey C, Bess J, et al. Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages. J Virol. 2006;80:9039-52 pubmed
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Raiborg C, Wesche J, Malerød L, Stenmark H. Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains. J Cell Sci. 2006;119:2414-24 pubmed
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Razi M, Futter C. Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation. Mol Biol Cell. 2006;17:3469-83 pubmed
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Almeida C, Takahashi R, Gouras G. Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system. J Neurosci. 2006;26:4277-88 pubmed
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Duncan L, Piper S, Dodd R, Saville M, Sanderson C, Luzio J, et al. Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J. 2006;25:1635-45 pubmed
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Bache K, Stuffers S, Malerød L, Slagsvold T, Raiborg C, Lechardeur D, et al. The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. Mol Biol Cell. 2006;17:2513-23 pubmed
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Gullapalli A, Wolfe B, Griffin C, Magnuson T, Trejo J. An essential role for SNX1 in lysosomal sorting of protease-activated receptor-1: evidence for retromer-, Hrs-, and Tsg101-independent functions of sorting nexins. Mol Biol Cell. 2006;17:1228-38 pubmed
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Irie T, Harty R. L-domain flanking sequences are important for host interactions and efficient budding of vesicular stomatitis virus recombinants. J Virol. 2005;79:12617-22 pubmed
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Katoh K, Suzuki H, Terasawa Y, Mizuno T, Yasuda J, Shibata H, et al. The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B. Biochem J. 2005;391:677-85 pubmed
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Cabezas A, Bache K, Brech A, Stenmark H. Alix regulates cortical actin and the spatial distribution of endosomes. J Cell Sci. 2005;118:2625-35 pubmed
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Irie T, Licata J, Harty R. Functional characterization of Ebola virus L-domains using VSV recombinants. Virology. 2005;336:291-8 pubmed
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Ward D, Vaughn M, Shiflett S, White P, Pollock A, Hill J, et al. The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. J Biol Chem. 2005;280:10548-55 pubmed
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Lin Y, Kimpler L, Naismith T, Lauer J, Hanson P. Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. J Biol Chem. 2005;280:12799-809 pubmed
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Bache K, Slagsvold T, Cabezas A, Rosendal K, Raiborg C, Stenmark H. The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. Mol Biol Cell. 2004;15:4337-46 pubmed
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Stuchell M, Garrus J, Muller B, Stray K, Ghaffarian S, McKinnon R, et al. The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. J Biol Chem. 2004;279:36059-71 pubmed
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Sharma M, Pampinella F, Nemes C, Benharouga M, So J, Du K, et al. Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes. J Cell Biol. 2004;164:923-33 pubmed
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Zhu G, Gilchrist R, Borley N, Chng H, Morgan M, Marshall J, et al. Reduction of TSG101 protein has a negative impact on tumor cell growth. Int J Cancer. 2004;109:541-7 pubmed
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Irie T, Licata J, McGettigan J, Schnell M, Harty R. Budding of PPxY-containing rhabdoviruses is not dependent on host proteins TGS101 and VPS4A. J Virol. 2004;78:2657-65 pubmed
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Heissmeyer V, Macian F, Im S, Varma R, Feske S, Venuprasad K, et al. Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nat Immunol. 2004;5:255-65 pubmed
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von Schwedler U, Stuchell M, Muller B, Ward D, Chung H, Morita E, et al. The protein network of HIV budding. Cell. 2003;114:701-13 pubmed
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Strack B, Calistri A, Craig S, Popova E, Gottlinger H. AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. Cell. 2003;114:689-99 pubmed
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Chiou C, Hu C, Chen P, Liao C, Lin Y, Wang J. Association of Japanese encephalitis virus NS3 protein with microtubules and tumour susceptibility gene 101 (TSG101) protein. J Gen Virol. 2003;84:2795-805 pubmed
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Gottwein E, Bodem J, Muller B, Schmechel A, Zentgraf H, Kräusslich H. The Mason-Pfizer monkey virus PPPY and PSAP motifs both contribute to virus release. J Virol. 2003;77:9474-85 pubmed
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Bache K, Brech A, Mehlum A, Stenmark H. Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J Cell Biol. 2003;162:435-42 pubmed
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Pornillos O, Higginson D, Stray K, Fisher R, Garrus J, Payne M, et al. HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J Cell Biol. 2003;162:425-34 pubmed
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Zhu G, Reynolds L, Crnogorac Jurcevic T, Gillett C, Dublin E, Marshall J, et al. Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer. Oncogene. 2003;22:3742-8 pubmed
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Myers E, Allen J. Tsg101, an inactive homologue of ubiquitin ligase e2, interacts specifically with human immunodeficiency virus type 2 gag polyprotein and results in increased levels of ubiquitinated gag. J Virol. 2002;76:11226-35 pubmed
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Bishop N, Horman A, Woodman P. Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates. J Cell Biol. 2002;157:91-101 pubmed
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Garrus J, von Schwedler U, Pornillos O, Morham S, Zavitz K, Wang H, et al. Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding. Cell. 2001;107:55-65 pubmed
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产品信息
目录号 :
GTX70255
产品名称 :
TSG101抗体[4A10]
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
一抗
规格 :
100.00μg
标价 :
299美元
Pubmed号列表 :
23616621,24227888,24105262,24101586,22102283,18190528,21757542,19307599,16973552,19808888,17475779,18267010,14990685,15007060,14505570,11916981,19158374,15240819,21482733,13679614,18256029,19682329,17984323,18768755,21931550,15644320,16940516,20691033,19624486,16188963,20023299,14505569,20974815,16601694,14973438,15632132,16474136,12900394,16407403,22031884,21113135,11595185,12388682,15218037,22711829,16554368,12802281,20720181,16720641,21951651,17760879,14991575,17468102,12915562,15914539,18817529,16624948,15892969,22315426,12900395,24009879,23077308,16707569,19520058,16004603,21136642,22969426,23733886,23813961,22416276,17895996,18767904,24792623,25510868
克隆 :
4A10
抗体亚型 :
IgG1
产品描述 :
小鼠单克隆抗体人类TSG101
交叉活性 :
Hu, Ms, Mk, Rat, Hm
背景 :
TSG101-4A10 recognizes TSG101 protein, the product of a recently identified Tumor Susceptibility Gene whose inactivation in mouse fibroblasts results in cell transformation and the ability of those cells to form tumors in nude mice. The TSG101 gene encodes a 46 kDa protein and contains a proline-rich domain and a luecine-zipper motif within a coiled-coil domain near the carboxyl terminus.
免疫原 :
Amino acids 167-374 of TSG101 protein expressed in E. coli.
缓冲液 :
磷酸盐缓冲液, pH值7.4, 含无防腐剂
用途 :
酶联免疫吸附测定, 流式细胞仪, 免疫细胞化学/IF, 免疫组化, 免疫组化-P, 免疫沉淀, 免疫印迹
浓度 :
1毫克/毫升
一般参考 :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
图像Legend_4 :
Immunohistochemical analysis of paraffin-embedded Colon carcinoma, using TSG101(GTX70255) antibody at 1:100 dilution.
图像Legend_5 :
Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: C2C12 10% SDS PAGE GTX70255 diluted at 1:500
图像Legend_6 :
TSG101 antibody [4A10] detects TSG101 protein by Western blot analysis. A. 30 µg 293T whole cell lysate/extract. B. 30 µg A431 whole cell lysate/extract. 10 % SDS-PAGE. TSG101 antibody [4A10] (GTX70255) dilution: 1:500
图像Legend_7 :
TSG101 antibody [4A10] detects TSG101 protein by Western blot analysis. A. 30 µg NIH-3T3 whole cell lysate/extract. B. 30 µg JC whole cell lysate/extract. C. 30 µg BCL-1 whole cell lysate/extract. 10 % SDS-PAGE. TSG101 antibody [4A10] (GTX70255) dilution: 1:500
更多信息或购买 :
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GeneTex
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