产品简要
信息索取 :
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
RPA32抗体
目录 :
GTX70258
规格 :
100.00μl
价格 :
289美元
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
文章摘录数: 5
已发表的文献中的应用方法/种属/稀释度参考文献
  • 免疫印迹; 人类
Nichols G, Schaack J, Ornelles D. Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication. J Virol. 2009;83:5987-98 pubmed 出版商
Adeyemi R, Pintel D. The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice. J Virol. 2014;88:10189-99 pubmed 出版商
Koundrioukoff S, Carignon S, Técher H, Letessier A, Brison O, Debatisse M. Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity. PLoS Genet. 2013;9:e1003643 pubmed 出版商
Draskovic I, Arnoult N, Steiner V, Bacchetti S, Lomonte P, Londono-Vallejo A. Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proc Natl Acad Sci U S A. 2009;106:15726-31 pubmed 出版商
Adeyemi R, Landry S, Davis M, Weitzman M, Pintel D. Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication. PLoS Pathog. 2010;6:e1001141 pubmed 出版商
图像
图像 1 :
GeneTex GTX70258 图像 1
GTXat a dilution of 1:2500 staining RPA 32 in A) HeLa whole cell lysate, B) Raji whole cell lysate and C) NIH-3T3 whole cell lysate by Western Blot (ECL)
图像 2 :
GeneTex GTX70258 图像 2
Detection of human RPA32 protein using GeneTex RPA32 polyclonal antiserum (GTX70258) in HeLa whole cell extract.
图像 3 :
GeneTex GTX70258 图像 3
RPA32 antibody detects RPA32 protein at DNA damage foci by immunofluorescent analysis. Sample: 2mM Hydroxyurea treated (right) or untreated (left) HeLa cells were fixed in ice-cold MeOH for 5 min. Green: RPA32 protein stained by RPA32 antibody (GTX70258) diluted at 1:2000. Blue: Hoechst 33342 staining.
产品信息
目录号 :
GTX70258
产品名称 :
RPA32抗体
宿主物种 :
克隆性 :
多克隆
产品类型 :
一抗
规格 :
100.00μl
标价 :
289美元
Pubmed号列表 :
19717459,20949077,19321613,24965470
抗体亚型 :
IgG
产品描述 :
Rabbit polyclonal antiserum to human RPA32
交叉活性 :
Hu, Ms
背景 :
Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase. The middle subunit, RPA-32, is phosphorylated during the S-phase of the cell cycle, in response to DNA damage and during apoptotsis of Jurkat T- lymphocytes.
免疫原 :
全长人类RPA-32在大肠杆菌中表达
缓冲液 :
磷酸盐缓冲液, pH值7.4, 含无防腐剂
用途 :
免疫细胞化学/IF, 免疫印迹
浓度 :
抗血清
一般参考 :
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国