产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
GFAP小鼠单克隆抗体[1-D4](EM140707)
目录 :
EM140707
规格 :
单克隆
价格 :
1-D4
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1-D4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
EM140707
产品名称 :
GFAP小鼠单克隆抗体[1-D4](EM140707)
类别 :
Mouse monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
1-D4
宿主 :
小鼠
应用 :
免疫印迹, 免疫组化-P, 免疫细胞化学, FC
应用w/稀释 :
WB: 1:2, 000-1:5, 000;ICC:1:200;免疫组化-P:1:200;FC:1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within C-terminal human GFAP.
抗体亚型 :
IgG1
靶蛋白 :
GFAP
靶标.UniProt数据库 :
P14136
靶标.同义词 :
wu:fb34h11 antibody; ALXDRD antibody; cb345 antibody; etID36982.3 antibody; FLJ42474 antibody; FLJ45472 antibody; GFAP antibody; GFAP_HUMAN antibody; gfapl antibody; Glial fibrillary acidic protein antibody; Intermediate filament protein antibody; wu:fk42c12 antibody; xx:af506734 antibody; zgc:110485 antibody
Target function/background :
Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes and ependymal cells during development. GFAP has also been found to be expressed in glomeruli and peritubular fibroblasts taken from rat kidneys, Leydig cells of the testis in both hamsters and humans, human keratinocytes, human osteocytes and chondrocytes and stellate cells of the pancreas and liver in rats. GFAP is closely related to the other three non-epithelial type III IF family members, vimentin, desmin and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength as well as the shape of cells, but its exact function remains poorly understood, despite the number of studies using it as a cell marker. There are multiple disorders associated with improper GFAP regulation, and injury can cause glial cells to react in detrimental ways. Glial scarring is a consequence of several neurodegenerative conditions, as well as injury that severs neural material. Another condition directly related to GFAP is Alexander disease, a rare genetic disorder. Notably, the expression of some GFAP isoforms have been reported to decrease in response to acute infection or neurodegeneration. Additionally, reduction in GFAP expression has also been reported in Wernicke's encephalopathy.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
2微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
50 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
329
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!