产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
CD130小鼠单克隆抗体[B11-B9-A8](EM1701-43)
目录 :
EM1701-43
规格 :
单克隆
价格 :
B11-B9-A8
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B11-B9-A8
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
EM1701-43
产品名称 :
CD130小鼠单克隆抗体[B11-B9-A8](EM1701-43)
类别 :
Mouse monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
B11-B9-A8
宿主 :
小鼠
应用 :
免疫印迹, 免疫组化-P, 免疫细胞化学
应用w/稀释 :
WB: 1:500-1:2, 000;ICC:1:50-1:200;免疫组化-P:1:50-1:200
反应物种 :
人类
免疫原 :
重组蛋白
抗体亚型 :
IgG2b
靶蛋白 :
CD130
靶标.UniProt数据库 :
P40189
靶标.同义词 :
CD130 antibody; CD130 antigen antibody; CDw130 antibody; gp130 antibody; GP130 RAPS antibody; IL 6R beta antibody; IL-6 receptor subunit beta antibody; IL-6R subunit beta antibody; IL-6R-beta antibody; IL-6RB antibody; IL6 ST antibody; IL6RB_HUMAN antibody; IL6ST antibody; Interleukin 6 receptor subunit beta antibody; Interleukin receptor beta chain antibody; Interleukin-6 receptor subunit beta antibody; Interleukin-6 signal transducer antibody; Membrane glycoprotein 130 antibody; Membrane glycoprotein gp130 antibody; Oncostatin M receptor antibody; Oncostatin M receptor alpha subunit antibody; Oncostatin-M receptor subunit alpha antibody
Target function/background :
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases. That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3. Mediates signals which regulate immune response, hematopoiesis, pain control and bone metabolism. Has a role in embryonic development. Does not bind IL6. Essential for survival of motor and sensory neurons and for differentiation of astrocytes. Required for expression of TRPA1 in nociceptive neurons. Required for the maintenance of PTH1R expression in the osteoblast lineage and for the stimulation of PTH-induced osteoblast differentiation. Required for normal trabecular bone mass and cortical bone composition.
产品形式 :
液体
纯化 :
蛋白质G亲和纯化
浓度 :
2微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
103 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
325
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!