产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
NQO1小鼠单克隆抗体[13A1](EM1801-21)
目录 :
EM1801-21
规格 :
单克隆
价格 :
13A1
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
13A1
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
EM1801-21
产品名称 :
NQO1小鼠单克隆抗体[13A1](EM1801-21)
类别 :
Mouse monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
13A1
宿主 :
小鼠
应用 :
免疫印迹, 免疫组化-P
应用w/稀释 :
WB:1:1, 000-1:5, 000;免疫组化-P:1:50
反应物种 :
人类, 大鼠
免疫原 :
Recombinant protein within Human NQO1 aa 1-285.
抗体亚型 :
IgG2b
靶蛋白 :
NQO1
靶标.UniProt数据库 :
P15559
靶标.同义词 :
Azoreductase antibody; Cytochrome b 5 reductase antibody; DHQU antibody; DIA 4 antibody; DIA4 antibody; Diaphorase (NADH/NADPH) (cytochrome b 5 reductase) antibody; Diaphorase (NADH/NADPH) antibody; Diaphorase 4 antibody; Dioxin inducible 1 antibody; DT diaphorase antibody; DT-diaphorase antibody; DTD antibody; Menadione reductase antibody; NAD(P)H dehydrogenase [quinone] 1 antibody; NAD(P)H dehydrogenase quinone 1 antibody; NAD(P)H menadione oxidoreductase 1 dioxin inducible antibody; NAD(P)H quinone dehydrogenase 1 antibody; NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1 antibody; NAD(P)H:menadione oxidoreductase 1 antibody; NAD(P)H:Quinone acceptor oxidoreductase type 1 antibody; NAD(P)H:quinone oxidoreductase 1 antibody; NAD(P)H:quinone oxireductase antibody; NMOR 1 antibody; NMOR I antibody; NMOR1 antibody; NMORI antibody; NQO 1 antibody; NQO1 antibody; NQO1_HUMAN antibody; Phylloquinone reductase antibody; QR 1 antibody; QR1 antibody; Quinone reductase 1 antibody
Target function/background :
NQO1, a 274 amino acid protein, is ubiquitously expressed, but the expression level varies among tissues. NQO1 gene expression is coordinately induced in response to xenobiotics, antioxidants, heavy metals and radiation. The antioxidant response element (ARE) in the NQO1 gene promoter is essential for expression and coordinated induction of NQO1. ARE activation by tert-butylhydroquinone is dependent on PI3-kinase, which lies upstream of Nrf2. Nrf2, c-Jun, Nrf1, Jun-B and Jun-D bind to the ARE and regulate expression and induction of NQO1 gene. Maf-Maf homodimers and possibly Maf-Nrf2 heterodimers play a role in negative regulation of ARE-mediated transcription, but Maf-Nrf1 heterodimers fail to bind with the NQO1 gene ARE and do not repress NQO1 transcription.
产品形式 :
液体
纯化 :
蛋白亲和纯化
浓度 :
2微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
31 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
325
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!