产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
组织蛋白酶D小鼠单克隆抗体[13F3](EM1901-02)
目录 :
EM1901-02
规格 :
单克隆
价格 :
13F3
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
13F3
反应物种 :
人类
应用 :
免疫印迹, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
EM1901-02
产品名称 :
组织蛋白酶D小鼠单克隆抗体[13F3](EM1901-02)
类别 :
Mouse monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
13F3
宿主 :
小鼠
应用 :
免疫印迹, 免疫组化-P
应用w/稀释 :
WB:1:10, 000-1:50, 000;免疫组化-P:1:50
反应物种 :
人类
免疫原 :
Recombinant protein within Human Cathepsin D aa 1-432.
抗体亚型 :
IgG1
靶蛋白 :
组织蛋白酶D
靶标.UniProt数据库 :
P07339
靶标.同义词 :
CatD antibody; CATD_HUMAN antibody; Cathepsin D antibody; Cathepsin D heavy chain antibody; CD antibody; Ceroid lipofuscinosis neuronal 10 antibody; CLN10 antibody; CPSD antibody; ctsd antibody; Epididymis secretory sperm binding protein Li 130P antibody; HEL S 130P antibody; Lysosomal aspartyl peptidase antibody; Lysosomal aspartyl protease antibody; MGC2311 antibody
Target function/background :
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
产品形式 :
液体
纯化 :
蛋白亲和纯化
浓度 :
2微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
28/43/46 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
325
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!