产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
CD40小鼠单克隆抗体[A1E5](EM1901-41)
目录 :
EM1901-41
规格 :
单克隆
价格 :
A1E5
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A1E5
反应物种 :
人类
应用 :
免疫印迹, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
EM1901-41
产品名称 :
CD40小鼠单克隆抗体[A1E5](EM1901-41)
类别 :
Mouse monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
A1E5
宿主 :
小鼠
应用 :
免疫印迹, 免疫组化-P, FC
应用w/稀释 :
WB:1:500-1:2, 000;免疫组化-P:1:50;FC:1:50-1:100
反应物种 :
人类
免疫原 :
Recombinant protein within human CD40 aa 1-250.
抗体亚型 :
IgG1
靶蛋白 :
CD40
靶标.UniProt数据库 :
P25942
靶标.同义词 :
AI326936 antibody; B cell associated molecule CD40 antibody; B cell surface antigen CD40 antibody; B cell-associated molecule antibody; B-cell surface antigen CD40 antibody; Bp50 antibody; CD 40 antibody; CD40 antibody; CD40 antigen (TNF receptor superfamily member 5) antibody; CD40 antigen antibody; CD40 molecule antibody; CD40 molecule, TNF receptor superfamily member 5 antibody; CD40 protein antibody; CD40 type II isoform antibody; CD40L receptor antibody; CDw40 antibody; GP39 antibody; HIGM1 antibody; IGM antibody; IMD3 antibody; MGC9013 antibody; Nerve growth factor receptor related B lymphocyte activation molecule antibody; OTTHUMP00000031699 antibody; OTTHUMP00000031700 antibody; p50 antibody; T-BAM antibody; TBAM antibody; TNF receptor superfamily member 5 antibody; TNFRSF5 antibody; TNR5_HUMAN antibody; TRAP antibody; Tumor necrosis factor receptor superfamily , member 5 antibody; Tumor necrosis factor receptor superfamily member 5 antibody; Tumor necrosis factor receptor superfamily member 5 precursor antibody; Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody
Target function/background :
This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
2微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
31 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
325
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!