产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
ERK2小鼠单克隆抗体[C3B12](EM1901-55)
目录 :
EM1901-55
规格 :
单克隆
价格 :
C3B12
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
C3B12
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
EM1901-55
产品名称 :
ERK2小鼠单克隆抗体[C3B12](EM1901-55)
类别 :
Mouse monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
C3B12
宿主 :
小鼠
应用 :
免疫印迹, 免疫组化-P, FC
应用w/稀释 :
WB: 1:500-1:2, 000;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠
免疫原 :
Recombinant protein within human ERK2 aa 200-360.
抗体亚型 :
IgG1
靶蛋白 :
ERK2
靶标.UniProt数据库 :
P28482
靶标.同义词 :
ERK 2 antibody; ERK-2 antibody; ERT1 antibody; Extracellular Signal Regulated Kinase 2 antibody; Extracellular signal-regulated kinase 2 antibody; MAP kinase 1 antibody; MAP kinase 2 antibody; MAP kinase isoform p42 antibody; MAPK 1 antibody; MAPK 2 antibody; Mapk1 antibody; MAPK2 antibody; Mitogen-activated protein kinase 1 antibody; Mitogen-activated protein kinase 2 antibody; MK01_HUMAN antibody; P38 antibody; P40 antibody; P41 antibody; p42-MAPK antibody; P42MAPK antibody; PRKM1 antibody; PRKM2 antibody; protein kinase, mitogen-activated, 1 antibody; protein kinase, mitogen-activated, 2 antibody; protein tyrosine kinase ERK2 antibody
Target function/background :
Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein-coupled receptor ligands, and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK1 and ERK2 requires phosphorylation by upstream kinases such as MAP kinase kinase (MEK), MEK kinase and Raf-1. ERK1 and ERK2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the Threonine-Glutamate-Tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development. The human ERK2 gene maps to chromosome 22q11.21 and encodes a 360-amino acid protein.
产品形式 :
液体
纯化 :
蛋白质G亲和纯化
浓度 :
2微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
41 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
325
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!