产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
小窝蛋白1小鼠单克隆抗体[A3E4](EM1902-01)
目录 :
EM1902-01
规格 :
单克隆
价格 :
A3E4
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A3E4
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
EM1902-01
产品名称 :
小窝蛋白1小鼠单克隆抗体[A3E4](EM1902-01)
类别 :
Mouse monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
A3E4
宿主 :
小鼠
应用 :
免疫印迹, 免疫组化-P, FC
应用w/稀释 :
WB:1:1, 000-1:2, 000;免疫组化-P:1:500, 000;FC:1:50-1:100
反应物种 :
人类, 小鼠
免疫原 :
Recombinant protein within human Caveolin-1 aa 1-150.
抗体亚型 :
IgG1
靶蛋白 :
小窝蛋白1
靶标.UniProt数据库 :
Q03135
靶标.同义词 :
BSCL3 antibody; CAV antibody; CAV1 antibody; CAV1_HUMAN antibody; caveolae protein, 22 kD antibody; caveolin 1 alpha isoform antibody; caveolin 1 beta isoform antibody; Caveolin 1 caveolae protein 22kDa antibody; Caveolin-1 antibody; Caveolin1 antibody; cell growth-inhibiting protein 32 antibody; CGL3 antibody; LCCNS antibody; MSTP085 antibody; OTTHUMP00000025031 antibody; PPH3 antibody; VIP 21 antibody; VIP21 antibody
Target function/background :
Caveolin-1 is a protein that in humans is encoded by the CAV1 gene. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. Caveolin 1 has been shown to interact with heterotrimeric G proteins, Src tyrosine kinases (Src, Lyn) and H-Ras, cholesterol, TGF beta receptor 1, endothelial NOS, androgen receptor, amyloid precursor protein, gap junction protein, alpha 1, nitric oxide synthase 2A, epidermal growth factor receptor, endothelin receptor type B, PDGFRB, PDGFRA, PTGS2, TRAF2, estrogen receptor alpha, caveolin 2, PLD2, Bruton's tyrosine kinase and SCP2. All these interactions are through a caveolin-scaffolding domain (CSD) within caveolin-1 molecule. Molecules that interact with caveolin-1 contain caveolin-binding motifs (CBM).
产品形式 :
液体
纯化 :
蛋白质G亲和纯化
浓度 :
2微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
20 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
329
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!