产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
Glut-1 Rabbit Polyclonal Antibody (ER1510-11)
目录 :
ER1510-11
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ER1510-11
产品名称 :
Glut-1 Rabbit Polyclonal Antibody (ER1510-11)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, FC
应用w/稀释 :
WB:1:500;ICC:1:100-1:500;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠
免疫原 :
Synthetic peptide within C-terminal human Glut-1.
抗体亚型 :
IgG
靶蛋白 :
Glut-1
靶标.UniProt数据库 :
P11166
靶标.同义词 :
Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity) antibody; CSE antibody; DYT17 antibody; DYT18 antibody; DYT9 antibody; EIG12 antibody; erythrocyte/brain antibody; Erythrocyte/hepatoma glucose transporter antibody; facilitated glucose transporter member 1 antibody; Glucose transporter 1 antibody; Glucose transporter type 1 antibody; Glucose transporter type 1, erythrocyte/brain antibody; GLUT antibody; GLUT-1 antibody; GLUT1 antibody; GLUT1DS antibody; GLUTB antibody; GT1 antibody; GTG1 antibody; Gtg3 antibody; GTR1_HUMAN antibody; HepG2 glucose transporter antibody; HTLVR antibody; Human T cell leukemia virus (I and II) receptor antibody; MGC141895 antibody; MGC141896 antibody; PED antibody; RATGTG1 antibody; Receptor for HTLV 1 and HTLV 2 antibody; SLC2A1 antibody; Solute carrier family 2 (facilitated glucose transporter), member 1 antibody; Solute carrier family 2 antibody; Solute carrier family 2, facilitated glucose transporter member 1 antibody
Target function/background :
Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter, Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane, and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve-pass transmembrane proteins (12TM) whose carboxy-termini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.
产品形式 :
液体
纯化 :
肽亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
54 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!