产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
PRTN3兔多克隆抗体(ER1706-25)
目录 :
ER1706-25
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ER1706-25
产品名称 :
PRTN3兔多克隆抗体(ER1706-25)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P
应用w/稀释 :
WB:1:500;ICC:1:50-1:200;免疫组化-P:1:100-1:500
反应物种 :
人类, 小鼠
免疫原 :
Recombinant protein within human PRTN3 aa 50-250.
抗体亚型 :
IgG
靶蛋白 :
PRTN3
靶标.UniProt数据库 :
P24158
靶标.同义词 :
ACPA antibody; AGP 7 antibody; AGP7 antibody; AGP7 serine proteinase antibody; Azurophil Granule Protein 7 antibody; C ANCA antibody; C ANCA antigen antibody; C-ANCA antigen antibody; CANCA antibody; EC 3.4.21.76 antibody; Leukocyte proteinase 3 antibody; MBN antibody; MBT antibody; MBT WEGENER AUTOANTIGEN antibody; Myeloblastin antibody; Neutrophil proteinase 4 antibody; NP 4 antibody; NP-4 antibody; NP4 antibody; P29 antibody; PR 3 antibody; PR-3 antibody; PR3 antibody; Proteinase 3 antibody; Proteinase3 antibody; PRTN 3 antibody; Prtn3 antibody; PRTN3_HUMAN antibody; Serine proteinase neutrophil Wegener granulomatosis autoantigen antibody; Serine proteinase, neutrophil antibody; Wegener autoantigen antibody; Wegener granulomatosis autoantigen antibody
Target function/background :
The major features of Wegener granulomatosis are necrotizing granulomatous lesions, which most often affect the upper and lower airways and are associated with vasculitis, necrotizing glomerulonephritis and pulmonary capillaritis. The antigen responsible for this disease is Proteinase 3 (PR3, P29 or myeloblastin), which is one of the antibiotic proteins of neutrophilic granules belonging to the serine protease family. It is closely related to two others: Neutrophil Elastase and azurocidin. All three genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. PR3 is a neutrophil protein which is able to cleave elastin and is involved in proliferation of human leukemia cells. PR3 is expressed specifically in immature myeloid cells and is a G-CSF-responsive protein critical to factor-independent growth. The genes for all three of the related serine protease family members are located in a cluster on the tip of the short arm of human chromosome 19.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
27 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!