产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
PP2C甲兔多克隆抗体(ER1706-37)
目录 :
ER1706-37
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ER1706-37
产品名称 :
PP2C甲兔多克隆抗体(ER1706-37)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, FC
应用w/稀释 :
WB:1:500;ICC:1:100-1:500;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Recombinant protein within human PP2C alpha aa 42-330.
抗体亚型 :
IgG
靶蛋白 :
PP2C甲
靶标.UniProt数据库 :
P35813
靶标.同义词 :
Protein phosphatase 2C isoform alpha antibody; EC 3.1.3.16 antibody; FLJ42306 antibody IA antibody; MGC9201 antibody; Mpp alpha antibody; PP2C alpha antibody; PP2C-alpha antibody; PP2CA antibody; PP2Calpha antibody; PPM 1A antibody; PPM1A antibody; PPM1A_HUMAN antibody; PPPM1A antibody; Protein phosphatase 1A (formerly 2C) magnesium dependent alpha isoform antibody; Protein phosphatase 1A antibody; Protein phosphatase 1A magnesium dependent alpha antibody; Protein phosphatase 2C alpha antibody; Protein phosphatase 2C alpha isoform antibody; Protein phosphatase 2C isoform alpha antibody; Protein phosphatase IA antibody; Protein phosphatase, Mg2+/Mn2+ dependent, 1A antibody
Target function/background :
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/ threonine protein phosphatases. Protein phosphatase 2Ca (PP2Ca) has broad specificity. It dephosphorylates and negatively regulates the activities of MAP kinases and MAP kinase-kinases while also inhibiting the activation of p38 and JNK kinase cascades, induced by environmental stresses. PP2Ca also induces the expression of endogenous p53 and the p53-responsive gene p21, leading to cell cycle arrest and apoptosis. The PP2Ca protein, which contains an active site containing a dinuclear metal ion center, shows highest expression in epithelial cells, as well as in the digestive tract, lung, kidney, breast, prostate, endocrine glands and brain.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
42/35 kDa, additional band 55 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!