产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
Toll样受体4兔多克隆抗体(ER1706-43)
目录 :
ER1706-43
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ER1706-43
产品名称 :
Toll样受体4兔多克隆抗体(ER1706-43)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
应用 :
免疫细胞化学, 免疫组化-P, FC, 免疫印迹
应用w/稀释 :
ICC:1:50-1:200;免疫组化-P:1:50-1:200;FC:1:50-1:100;WB:1:500
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human TLR4 aa 766-820.
抗体亚型 :
IgG
靶蛋白 :
Toll样受体4
靶标.UniProt数据库 :
O00206
靶标.同义词 :
ARMD10 antibody; CD284 antibody; CD284 antigen antibody; Homolog of Drosophila toll antibody; hToll antibody; TLR 4 antibody; TLR4 antibody; TLR4_HUMAN antibody; TOLL antibody; Toll like receptor 4 antibody; Toll-like receptor 4 antibody
Target function/background :
Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated toll-like receptors (TLR). Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo and participate in the host immunity. The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll / IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macro-phages, and TLR6 is highly homologous to TLR1, sharing greater than 65% sequence identity, and, like other members of TLR family, it induces NFkB signaling upon activation.
产品形式 :
液体
纯化 :
肽亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
96/91/73 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!