产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
NLRP3兔多克隆抗体(ER1706-72)
目录 :
ER1706-72
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ER1706-72
产品名称 :
NLRP3兔多克隆抗体(ER1706-72)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, FC
应用w/稀释 :
WB: 1:500-1:2, 000;ICC: 1:500-1:2, 000;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠
免疫原 :
Synthetic peptide within C-terminal human NLRP3.
抗体亚型 :
IgG
靶蛋白 :
NLRP3
靶标.UniProt数据库 :
Q96P20
靶标.同义词 :
AGTAVPRL antibody; AII/AVP antibody; Angiotensin/vasopressin receptor AII/AVP like antibody; Angiotensin/vasopressin receptor AII/AVP-like antibody; C1orf7 antibody; Caterpiller protein 1.1 antibody; CIAS 1 antibody; CIAS1 antibody; CLR1.1 antibody; Cold autoinflammatory syndrome 1 antibody; Cold autoinflammatory syndrome 1 protein antibody; Cryopyrin antibody; Familial cold autoinflammatory syndrome antibody; FCAS antibody; FCU antibody; LRR and PYD domains-containing protein 3 antibody; Muckle-Wells syndrome antibody; MWS antibody; NACHT antibody; NACHT LRR and PYD containing protein 3 antibody; NALP 3 antibody; NALP3 antibody; NALP3_HUMAN antibody; NLR family pyrin domain containing 3 antibody; NLRP3 antibody; PYPAF 1 antibody; PYPAF1 antibody; PYRIN containing APAF1 like protein 1 antibody; PYRIN-containing APAF1-like protein 1 antibody
Target function/background :
Cryopyrin interacts selectively with apoptosis associated specklike protein containing a CARD domain (ASC). This complex may function as an upstream activator of NFkB signaling and caspase-1 activation. The complex also inhibits TNFa induced activation and nuclear translocation of RelA/NFkB p65. Mutations in Cryopyrin and Pyrin proteins are responsible for several autoinflammatory disorders in humans, including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and chronic infantile neurologic cutaneous and articular syndrome (CINCA).
产品形式 :
液体
纯化 :
肽亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
85 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!