产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
孕酮受体兔多克隆抗体(ER1901-96)
目录 :
ER1901-96
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
产品信息
Catalog# :
ER1901-96
产品名称 :
孕酮受体兔多克隆抗体(ER1901-96)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, FC
应用w/稀释 :
WB: 1:500-1:2000;ICC: 1:100-1:500;FC: 1:50-1:100
反应物种 :
人类
免疫原 :
Recombinant protein within Human Progesterone receptor aa 30-250.
抗体亚型 :
IgG
靶蛋白 :
孕激素受体
靶标.UniProt数据库 :
P06401
靶标.同义词 :
NR3C3 antibody; Nuclear receptor subfamily 3 group C member 3 antibody; PGR antibody; PR antibody; PRA antibody; PRB antibody; PRGR_HUMAN antibody; Progesterone receptor antibody; Progestin receptor form A antibody; Progestin receptor form B antibody
Target function/background :
The effects of progesterone are mediated by two functionally different isoforms of the progesterone receptor, PR-A and PR-B, which are transcribed from distinct, estrogen-inducible promoters within a single copy of the PR gene. The first 164 amino acids of PR-B are absent in PR-A. Progesterone-bound PR-A and PR-B have different transcription activation properties. Specifically, PR-B functions as a transcriptional activator in most cell and promoter contexts, while PR-A is transcriptionally inactive and functions as a strong ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity. An inhibitory domain (ID), which maps to the amino terminus of the receptor, exists within both PR isoforms. Interestingly, the ID is functionally active only in PR-A and is necessary for steroid hormone transrepression by PR-A, suggesting that PR-A and PR-B may have different conformations in the cell.
产品形式 :
液体
纯化 :
蛋白亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
Predicted band size 99 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!