产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
cMet Rabbit Polyclonal Antibody (ER40501)
目录 :
ER40501
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ER40501
产品名称 :
cMet Rabbit Polyclonal Antibody (ER40501)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, FC
应用w/稀释 :
WB: 1:1, 000;ICC:1:200;免疫组化-P:1:200;FC:1:100-1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within mouse cMet aa 652-696.
抗体亚型 :
IgG
靶蛋白 :
cMet
靶标.UniProt数据库 :
P16056
靶标.同义词 :
AUTS9 antibody; c met antibody; D249 antibody; Hepatocyte growth factor receptor antibody; HGF antibody; HGF receptor antibody; HGF/SF receptor antibody; HGFR antibody; MET antibody; Met proto oncogene tyrosine kinase antibody; MET proto oncogene, receptor tyrosine kinase antibody; Met proto-oncogene (hepatocyte growth factor receptor) antibody; Met proto-oncogene antibody; Met protooncogene antibody; MET_HUMAN antibody; Oncogene MET antibody; Par4 antibody; Proto-oncogene c-Met antibody; RCCP2 antibody; Scatter factor receptor antibody; SF receptor antibody; Tyrosine-protein kinase Met antibody
Target function/background :
c-Met (MET or MNNG HOS Transforming gene) is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). MET is a membrane receptor that is essential for embryonic development and wound healing. Hepatocyte growth factor (HGF) is the only known ligand of the MET receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF is restricted to cells of mesenchymal origin. Upon HGF stimulation, MET induces several biological responses that collectively give rise to a program known as invasive growth. Abnormal MET activation in cancer correlates with poor prognosis, where aberrantly active MET triggers tumor growth, formation of new blood vessels (angiogenesis) that supply the tumor with nutrients, and cancer spread to other organs (metastasis). MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain.
产品形式 :
液体
纯化 :
肽亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
153 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!