产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
细胞周期蛋白D1重组兔单克隆抗体[SA38-08](ET1601-31)
目录 :
ET1601-31
规格 :
单克隆
价格 :
SA38-08
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SA38-08
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 2
出版应用/物种/样本/稀释 | 参考文献 |
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产品信息
Catalog# :
ET1601-31
产品名称 :
细胞周期蛋白D1重组兔单克隆抗体[SA38-08](ET1601-31)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SA38-08
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, 免疫沉淀
应用w/稀释 :
WB: 1:500-1:5, 000;免疫细胞化学/IF:1:50-1:200;免疫组化-P:1:50-1:200;IP:依实验方法而定
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within C-terminal human Cyclin D1.
抗体亚型 :
IgG
靶蛋白 :
细胞周期蛋白D1
靶标.UniProt数据库 :
P24385
靶标.同义词 :
AI327039 antibody; B cell CLL/lymphoma 1 antibody; B cell leukemia 1 antibody; B cell lymphoma 1 protein antibody; B-cell lymphoma 1 protein antibody; BCL 1 antibody; BCL-1 antibody; BCL-1 oncogene antibody; BCL1 antibody; BCL1 oncogene antibody; ccnd1 antibody; CCND1/FSTL3 fusion gene, included antibody; CCND1/IGHG1 fusion gene, included antibody; CCND1/IGLC1 fusion gene, included antibody; CCND1/PTH fusion gene, included antibody; CCND1_HUMAN antibody; cD1 antibody; Cyl 1 antibody; D11S287E antibody; G1/S specific cyclin D1 antibody; G1/S-specific cyclin-D1 antibody; Parathyroid adenomatosis 1 antibody; PRAD1 antibody; PRAD1 oncogene antibody; U21B31 antibody
Target function/background :
The proliferation of eukaryotic cells is controlled at specific points in the cell cycle, particularly at the G1 to S and the G2 to M transitions. It is well established that the Cdc2 p34-cyclin B protein kinase plays a critical role in the G2 to M transition while cyclin A associates with Cdk2 p33 and functions in S phase. Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
34 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
359
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!
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