产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
beta连环蛋白重组兔单克隆抗体[SA30-04](ET1601-5)
目录 :
ET1601-5
规格 :
单克隆
价格 :
SA30-04
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SA30-04
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
HUABIO 产品网页
文章摘录数: 2
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Xiang X, Xiong R, Yu C, Deng L, Bie J, Xiao D, et al. Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β‑catenin pathway. Oncol Rep. 2019;42:2600-2610 pubmed 出版商
  • 免疫印迹; 人类
Chen C, Wang Y, Zhong K, Jiang C, Wang L, Yuan Z, et al. Frequent B7-H3 overexpression in craniopharyngioma. Biochem Biophys Res Commun. 2019;: pubmed 出版商
产品信息
Catalog# :
ET1601-5
产品名称 :
beta连环蛋白重组兔单克隆抗体[SA30-04](ET1601-5)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SA30-04
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, 免疫沉淀
应用w/稀释 :
WB: 1:500-1:5, 000;ICC:1:20-1:50免疫组化-P:1:20-1:200;IP:依实验方法而定
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human Beta-Catenin aa 30-70.
抗体亚型 :
IgG
靶蛋白 :
beta连环蛋白
靶标.UniProt数据库 :
P35222
靶标.同义词 :
Beta catenin antibody; Beta-catenin antibody; Cadherin associated protein antibody; Catenin (cadherin associated protein), beta 1, 88kDa antibody; Catenin beta 1 antibody; Catenin beta-1 antibody; CATNB antibody; CHBCAT antibody; CTNB1_HUMAN antibody; CTNNB antibody; CTNNB1 antibody; DKFZp686D02253 antibody; FLJ25606 antibody; FLJ37923 antibody; OTTHUMP00000162082 antibody; OTTHUMP00000165222 antibody; OTTHUMP00000165223 antibody; OTTHUMP00000209288 antibody; OTTHUMP00000209289 antibody
Target function/background :
β-Catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. Phosphorylation at Ser-552 by AMPK promotes stabilizion of the protein, enhancing TCF/LEF-mediated transcription. Phosphorylation on Tyr-654 decreases CDH1 binding and enhances TBP binding. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
85 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
HUABIO 产品网页
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!