产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
磷酸化c(T58+S62)重组兔单克隆抗体[SZ02-06](ET1603-24)
目录 :
ET1603-24
规格 :
单克隆
价格 :
SZ02-06
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
SZ02-06
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
产品信息
Catalog# :
ET1603-24
产品名称 :
磷酸化c(T58+S62)重组兔单克隆抗体[SZ02-06](ET1603-24)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SZ02-06
宿主 :
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫沉淀
应用w/稀释 :
WB: 1:1, 000;免疫细胞化学/IF:1:50-1:200
反应物种 :
人类, 大鼠
免疫原 :
Synthetic phospho-peptide corresponding to residues surrounding Thr58 and Ser62 of human c-Myc.
抗体亚型 :
IgG
靶蛋白 :
磷酸化c(T58+S62)
靶标.UniProt数据库 :
P01106
靶标.同义词 :
Avian myelocytomatosis viral oncogene homolog antibody; bHLHe39 antibody; c Myc antibody; Class E basic helix-loop-helix protein 39 antibody; MRTL antibody; Myc antibody; Myc protein antibody; Myc proto oncogene protein antibody; Myc proto-oncogene protein antibody; myc related translation/localization regulatory factor antibody; MYC_HUMAN antibody; Myc2 antibody; MYCC antibody; Niard antibody; Nird antibody; Proto-oncogene c-Myc antibody; Transcription factor p64 antibody; v myc avian myelocytomatosis viral oncogene homolog antibody; v myc myelocytomatosis viral oncogene homolog antibody
Target function/background :
c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The L-Myc gene has been reported to be amplified and expressed at high level in human small cell lung carcinomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function. A basic region helix-loop-helix leucine zipper motif (bHLH-Zip) protein, designated Max, specifically associates with c-Myc, N-Myc and L-Myc proteins. The Myc-Max complex binds to DNA in a sequence-specific manner under conditions where neither Max nor Myc exhibit appreciable binding. Max can also form heterodimers with at least two additional bHLH-Zip proteins, Mad and Mxi1, and Mad-Max dimers have been shown to repress transcription through interaction with mSin3.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
49 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!