产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
细胞角蛋白18重组兔单克隆抗体[SZ80-07](ET1603-8)
目录 :
ET1603-8
规格 :
单克隆
价格 :
SZ80-07
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SZ80-07
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1603-8
产品名称 :
细胞角蛋白18重组兔单克隆抗体[SZ80-07](ET1603-8)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SZ80-07
宿主 :
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, FC
应用w/稀释 :
WB: 1:10, 000-1:50, 000;免疫细胞化学/IF:1:100-1:500;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Recombinant protein within mouse Cytokeratin 18 aa 200-423.
抗体亚型 :
IgG
靶蛋白 :
细胞角蛋白18
靶标.UniProt数据库 :
P05783
靶标.同义词 :
Cell proliferation inducing gene 46 protein antibody; Cell proliferation inducing protein 46 antibody; Cell proliferation-inducing gene 46 protein antibody; CK 18 antibody; CK-18 antibody; CK18 antibody; CYK 18 antibody; CYK18 antibody; Cytokeratin 18 antibody; Cytokeratin endo B antibody; Cytokeratin-18 antibody; K 18 antibody; K18 antibody; K1C18_HUMAN antibody; KA18 antibody; Keratin 18 antibody; Keratin 18, type I antibody; Keratin D antibody; keratin, type I cytoskeletal 18 antibody; Keratin-18 antibody; Krt18 antibody
Target function/background :
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, Cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while Cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas. Cytokeratin 18 contains two major phosphorylation sites on Ser 33 and Ser 52. Phosphorylation of Ser 18 is essential for the association of Cytokeratin 18 with 14-3-3 proteins and is involved in keratin organization and distribution.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
48 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!