产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
CD11c重组兔单克隆抗体[SI19-06](ET1606-19)
目录 :
ET1606-19
规格 :
单克隆
价格 :
SI19-06
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SI19-06
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1606-19
产品名称 :
CD11c重组兔单克隆抗体[SI19-06](ET1606-19)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SI19-06
宿主 :
兔
应用 :
免疫印迹, 免疫组化-P, 免疫沉淀
应用w/稀释 :
WB: 1:1, 000-1:2, 000;免疫组化-P:1:50-1:200
反应物种 :
人类
免疫原 :
Synthetic peptide within C-terminal human CD11c.
抗体亚型 :
IgG
靶蛋白 :
CD11c
靶标.UniProt数据库 :
P20702
靶标.同义词 :
95 alpha chain antibody; 95 antibody; CD 11c antibody; CD11 antigen-like family member C antibody; CD11c antibody; CD11c antigen antibody; Complement component 3 receptor 4 subunit antibody; CR4 antibody; Integrin alpha X antibody; Integrin alpha X chain antibody; Integrin alpha-X antibody; Integrin aX antibody; Integrin subunit alpha X antibody; integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody; integrin, alpha X (complement component 3 receptor 4 subunit antibody; ITAX_HUMAN antibody; ITGAX antibody; LEU M5 alpha subunit antibody; Leu M5 antibody; Leukocyte adhesion glycoprotein p150 95 alpha chain antibody; Leukocyte adhesion glycoprotein p150 antibody; Leukocyte adhesion receptor p150 95 antibody; Leukocyte adhesion receptor p150 antibody; Leukocyte surface antigen p150 95 alpha subunit antibody; Leukocyte surface antigen p150 alpha subunit antibody; Myeloid membrane antigen alpha subunit antibody; p150 95 integrin alpha chain antibody; p150 antibody; p150/95 antibody; SLEB6 antibody
Target function/background :
Integrin αX (CD11C, leukocyte surface antigen p150,95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with β2 chain to form a leukocyte-specific integrin known as inactivated-C3b (iC3b) receptor 4 (CR4). Integrin αX/β2 shares similar properties of the αM/β2 integrin in mediating adherence of neutrophils and monocytes to stimulated endothelial cells, and in phagocytosis of complement coated particles. Abnormal expression of Integrin αX is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of proto-oncogenes Ras and JunD. Proteins and DNA elements that influence transcription of Integrin αX include Sp1 and Sp1-like factors, AP-1 family, C/EBP, Oct-2 and PU.1. Integrin αX is present on monocyte derivative dendritic cells (DCs), macrophages and NK cells. Upon activation, DCs present in skin (Langerhans cells), lining of nose, lung, stomach, intestine and blood can migrate to lymphoid tissues and interact with T and B cells to initiate and shape the immune response.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
128 kDa(Predicted)
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!