产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
核纤层蛋白B1重组兔单克隆抗体[SI17-06](ET1606-27)
目录 :
ET1606-27
规格 :
单克隆
价格 :
SI17-06
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SI17-06
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
HUABIO 产品网页
文章摘录数: 1
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Lin X, Ma Y, Cai Z, Wang Q, Wang L, Huo Z, et al. Next-generation sequencing identified novel Desmoplakin frame-shift variant in patients with Arrhythmogenic cardiomyopathy. BMC Cardiovasc Disord. 2020;20:74 pubmed 出版商
产品信息
Catalog# :
ET1606-27
产品名称 :
核纤层蛋白B1重组兔单克隆抗体[SI17-06](ET1606-27)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SI17-06
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, 免疫沉淀
应用w/稀释 :
WB: 1:1, 000;免疫细胞化学/IF:1:50-1:200;免疫组化-P:1:100-1:500
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human Lamin B1 aa 520-560.
抗体亚型 :
IgG
靶蛋白 :
核纤层蛋白B1
靶标.UniProt数据库 :
P20700
靶标.同义词 :
ADLD抗体;核纤层蛋白B1抗体;核纤层蛋白B1抗体;LMN抗体;LMN2抗体;LMNB抗体;Lmnb1抗体;LMNB1_HUMAN抗体;MGC111419抗体;OTTHUMP00000159218抗体
Target function/background :
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
70 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
HUABIO 产品网页
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!