产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
CD86重组兔单克隆抗体[SJ20-00](ET1606-50)
目录 :
ET1606-50
规格 :
单克隆
价格 :
SJ20-00
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SJ20-00
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1606-50
产品名称 :
CD86重组兔单克隆抗体[SJ20-00](ET1606-50)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SJ20-00
宿主 :
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, 免疫沉淀, FC
应用w/稀释 :
WB: 1:1, 000-1:2, 000;免疫细胞化学/IF:1:50-1:200;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
Human,Rat,Monkey
免疫原 :
Synthetic peptide within human CD86 aa 1-40.
抗体亚型 :
IgG
靶蛋白 :
CD86
靶标.UniProt数据库 :
P42081
靶标.同义词 :
Activation B7-2 antigen 3 antibody; Activation B7-2 antigen antibody; B-lymphocyte activation antigen B7-2 2 antibody; B-lymphocyte activation antigen B7-2 antibody; B7 2 antibody; B7 antibody; B7-2 antibody; B7.2 antibody; B70 antibody; B72 antigen antibody; BU63 antibody; CD28 antigen ligand 2 2 antibody; CD28 antigen ligand 2 antibody; Cd28l2 antibody; CD28LG2 antibody; CD86 antibody; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 antibody; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) antibody; CD86 antigen antibody; CD86 molecule antibody; CD86_HUMAN antibody; CLS1 antibody; CTLA-4 counter-receptor B7.2 2, 3 antibody; CTLA-4 counter-receptor B7.2 antibody; Early T-cell costimulatory molecule 1 antibody; ETC-1 antibody; FUN 1 antibody; FUN-1 antibody; LAB72 antibody; Ly-58 antibody; Ly58 antibody; MB7 antibody; MB7-2 antibody; Membrane glycoprotein antibody; MGC34413 antibody; T-lymphocyte activation antigen CD86 antibody; TS/A-2 antibody
Target function/background :
T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins B7-1 (CD80) and B7-2 (CD86) expressed on antigen presenting cells bind the homologous T cell receptors CD28 and CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28, and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counterreceptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
70 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!