产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
Notch 1 Recombinant Rabbit Monoclonal Antibody [SJ205] (ET1606-55)
目录 :
ET1606-55
规格 :
单克隆
价格 :
SJ205
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SJ205
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1606-55
产品名称 :
Notch 1 Recombinant Rabbit Monoclonal Antibody [SJ205] (ET1606-55)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SJ205
宿主 :
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, 免疫沉淀, FC
应用w/稀释 :
WB: 1:1, 000-1:2, 000;免疫细胞化学/IF:1:50-1:200;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠
免疫原 :
Synthetic peptide within human Notch 1 aa 2500-2540.
抗体亚型 :
IgG
靶蛋白 :
Notch 1
靶标.UniProt数据库 :
P46531
靶标.同义词 :
9930111A19Rik antibody; AOS5 antibody; AOVD1 antibody; hN1 antibody; Lin-12 antibody; LIN12 antibody; Mis6 antibody; Motch A antibody; mT14 antibody; Neurogenic locus notch homolog protein 1 antibody; Neurogenic locus notch protein homolog antibody; NICD antibody; NOTC1_HUMAN antibody; Notch 1 antibody; Notch 1 intracellular domain antibody; NOTCH antibody; Notch gene homolog 1 (Drosophila) antibody; Notch homolog 1, translocation-associated (Drosophila) antibody; NOTCH, Drosophila, homolog of, 1 antibody; notch1 antibody; TAN1 antibody; Translocation associated notch homolog antibody; Translocation associated notch protein TAN 1 antibody; Translocation-associated notch protein TAN-1 antibody; xotch antibody
Target function/background :
The LIN-12/notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. To date, four notch homologs have been identified in mammals and have been designated Notch 1, Notch 2, Notch 3 and Notch 4. The notch genes are expressed in a variety of tissues in both the embryonic and adult organism, suggesting that the genes are involved in multiple signaling pathways. The notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for notch include Jagged1, Jagged2 and Delta. Jagged can activate notch and prevent myoblast differentiation by inhibiting the expression of muscle regulatory and structural genes. Jagged2 is thought to be involved in the development of various tissues whose development is dependent upon epithelial-mesenchymal interactions. Normal Delta expression is restricted to the adrenal gland and placenta. Delta expression has also been found in neuroendocrine tumors such as neuroblastomas and pheochromocytomas.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
125 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!