产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
DIABLO重组兔单克隆抗体[SC67-06](ET1610-74)
目录 :
ET1610-74
规格 :
单克隆
价格 :
SC67-06
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SC67-06
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1610-74
产品名称 :
DIABLO重组兔单克隆抗体[SC67-06](ET1610-74)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SC67-06
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, 免疫沉淀, FC
应用w/稀释 :
WB: 1:1, 000-1:2, 000;免疫细胞化学/IF:1:50-1:200;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
重组蛋白
抗体亚型 :
IgG
靶蛋白 :
DIABLO
靶标.UniProt数据库 :
Q9NR28
靶标.同义词 :
0610041G12Rik antibody; DBLOH_HUMAN antibody; DBOH antibody; DFNA64 antibody; diablo antibody; Diablo homolog (Drosophila) antibody; Diablo homolog antibody; Diablo homolog mitochondrial antibody; Diablo IAP binding mitochondrial protein antibody; Diablo like protein antibody; DIABLO S antibody; Direct IAP binding protein with low pI antibody; Direct IAP-binding protein with low pI antibody; FLJ10537 antibody; FLJ25049 antibody; mitochondrial antibody; Mitochondrial Smac protein antibody; Second mitochondria derived activator of caspase antibody; Second mitochondria-derived activator of caspase antibody; SMAC 3 antibody; Smac antibody; Smac protein antibody; SMAC3 antibody
Target function/background :
The activation of caspases is a key regulatory step in apoptosis. Once cytochrome c is released from the mitochondria into the cytosol, it binds Apaf-1 to form an oligomeric cytochrome c/Apaf-1 complex, which induces caspase activation. Inhibitors of Apoptosis Proteins (IAPs), are a family of proteins that regulate the cytochrome c/Apaf-1 caspase activating pathway. Like cytochrome c, Smac (for second mitochondria-derived activator of caspase, also designated DIABLO in mouse for direct IAP binding protein with low PI) promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding IAPs and preventing them from inhibiting caspases. In healthy cells, Smac is a mitochondrial protein, but when cells undergo apoptosis, Smac is released into the cytosol.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
21 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!