产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
ATG5重组兔单克隆抗体[SN73-07](ET1611-38)
目录 :
ET1611-38
规格 :
单克隆
价格 :
SN73-07
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SN73-07
反应物种 :
sea monkeys, 人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
HUABIO 产品网页
文章摘录数: 6
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类
Chen L, Yang Y, Bao J, Wang Z, Xia M, Dai A, et al. Autophagy negative-regulating Wnt signaling enhanced inflammatory osteoclastogenesis from Pre-OCs in vitro. Biomed Pharmacother. 2020;126:110093 pubmed 出版商
  • 免疫印迹; 人类
Sheng Y, Song Y, Li Z, Wang Y, Lin H, Cheng H, et al. RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly. Cell Death Differ. 2018;25:918-934 pubmed 出版商
  • 免疫印迹; sea monkeys
Lin C, Jia S, Yang F, Jia W, Yu X, Yang J, et al. The transcription factor p8 regulates autophagy during diapause embryo formation in Artemia parthenogenetica. Cell Stress Chaperones. 2016;21:665-75 pubmed 出版商
Fang Y, An N, Zhu L, Gu Y, Qian J, Jiang G, et al. Autophagy-Sirt3 axis decelerates hematopoietic aging. Aging Cell. 2020;19:e13232 pubmed 出版商
Wang W, Yang X, Chen Q, Guo M, Liu S, Liu J, et al. Sinomenine attenuates septic-associated lung injury through the Nrf2-Keap1 and autophagy. J Pharm Pharmacol. 2020;72:259-270 pubmed 出版商
Zhang W, Lei Z, Meng J, Li G, Zhang Y, He J, et al. Water Extract of Sporoderm-Broken Spores of Ganoderma lucidum Induces Osteosarcoma Apoptosis and Restricts Autophagic Flux. Onco Targets Ther. 2019;12:11651-11665 pubmed 出版商
产品信息
Catalog# :
ET1611-38
产品名称 :
ATG5重组兔单克隆抗体[SN73-07](ET1611-38)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SN73-07
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, 免疫沉淀
应用w/稀释 :
WB: 1:1, 000-1:5, 000;免疫细胞化学/IF:1:100-1:500;免疫组化-P:1:50-1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human ATG5 aa 10-50.
抗体亚型 :
IgG
靶蛋白 :
ATG5
靶标.UniProt数据库 :
Q9H1Y0
靶标.同义词 :
APG 5 antibody; APG 5L antibody; APG5 antibody; APG5 autophagy 5 like antibody; APG5 like antibody; APG5-like antibody; APG5L antibody; Apoptosis specific protein antibody; Apoptosis-specific protein antibody; ASP antibody; ATG 5 antibody; Atg5 antibody; ATG5 autophagy related 5 homolog antibody; ATG5_HUMAN antibody; Autophagy protein 5 antibody; Autophagy related 5 antibody; hAPG5 antibody; Homolog of S Cerevisiae autophagy 5 antibody; OTTHUMP00000040507 antibody
Target function/background :
Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
55 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
HUABIO 产品网页
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!