产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
BTK重组兔单克隆抗体[SN69-07](ET1611-4)
目录 :
ET1611-4
规格 :
单克隆
价格 :
SN69-07
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SN69-07
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
产品信息
Catalog# :
ET1611-4
产品名称 :
BTK重组兔单克隆抗体[SN69-07](ET1611-4)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SN69-07
宿主 :
兔
应用 :
免疫印迹, 免疫沉淀
应用w/稀释 :
WB: 1:1, 000-1:2, 000
反应物种 :
人类
免疫原 :
Synthetic peptide within C-terminal human BTK.
抗体亚型 :
IgG
靶蛋白 :
BTK
靶标.UniProt数据库 :
Q06187
靶标.同义词 :
Agammaglobulinaemia tyrosine kinase antibody; AGMX 1 antibody; AGMX1 antibody; AT antibody; ATK antibody; B cell progenitor kinase antibody; B-cell progenitor kinase antibody; BPK antibody; Bruton agammaglobulinemia tyrosine kinase antibody; Bruton tyrosine kinase antibody; Bruton’s Tyrosine Kinase antibody; Btk antibody; BTK_HUMAN antibody; dominant-negative kinase-deficient Brutons tyrosine kinase antibody; IMD 1 antibody; IMD1 antibody; MGC126261 antibody; MGC126262 antibody; OTTHUMP00000063593 antibody; PSCTK 1 antibody; PSCTK1 antibody; truncated Bruton agammaglobulinemia tyrosine kinase antibody; Tyrosine protein kinase BTK antibody; Tyrosine-protein kinase BTK antibody; tyrosine-protein kinase BTK isoform (lacking exon 14 antibody; XLA antibody
Target function/background :
The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton's disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
76 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!