产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
PARK7/DJ1重组兔单克隆抗体[SN07-21](ET1611-45)
目录 :
ET1611-45
规格 :
单克隆
价格 :
SN07-21
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
SN07-21
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1611-45
产品名称 :
PARK7/DJ1重组兔单克隆抗体[SN07-21](ET1611-45)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
SN07-21
宿主 :
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, 免疫沉淀, FC
应用w/稀释 :
WB: 1:1, 000-1:2, 000;免疫细胞化学/IF:1:100-1:500;免疫组化-P:1:100-1:500;FC:1:50-1:100
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human PARK7 aa 20-60.
抗体亚型 :
IgG
靶蛋白 :
PARK7/DJ1
靶标.UniProt数据库 :
Q99497
靶标.同义词 :
CAP1 antibody; DJ-1 antibody; DJ1 antibody; DJ1 protein antibody; Epididymis secretory sperm binding protein Li 67p antibody; FLJ27376 antibody; FLJ34360 antibody; FLJ92274 antibody; HEL S 67p antibody; Oncogene DJ1 antibody; OTTHUMP00000001348 antibody; OTTHUMP00000001349 antibody; OTTHUMP00000001350 antibody; OTTHUMP00000001351 antibody; PARK7 antibody; PARK7_HUMAN antibody; Parkinson disease (autosomal recessive, early onset) 7 antibody; Parkinson disease protein 7 antibody; Parkinson protein 7 antibody; Protein DJ-1 antibody; SP22 antibody
Target function/background :
PARK7/DJ1 is a ubiquitously expressed protein involved in various cellular processes including cell proliferation, RNA-binding, and oxidative stress. The protein has been found to colocalize within a subset of pathologic tau inclusions in a diverse group of neurodegenerative disorders known as tauopathies. Defects in PARK7/DJ1 are the cause of autosomal recessive early-onset Parkinson's disease 7 (PARK7). Parkinson's disease (PD) is a complex, multifactorial disorder that typically manifests after the age of 50 years. The disease is characterized by bradykinesia, resting tremor, muscular rigidity and postural instability. The pathology involves the loss of dopaminergic neurons in the substantia nigra and the presence of Lewy bodies (intraneuronal accumulations of aggregated proteins), in surviving neurons in various areas of the brain. PARK7 is characterized by onset before 40 years and slow progression. It has also been suggested that PARK7/DJ1 is a mitogen dependent oncogene product involved in Ras related signal transduction pathways.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
20 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!