产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
SOD2重组兔单克隆抗体[JJ089-02](ET1701-54)
目录 :
ET1701-54
规格 :
单克隆
价格 :
JJ089-02
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JJ089-02
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1701-54
产品名称 :
SOD2重组兔单克隆抗体[JJ089-02](ET1701-54)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JJ089-02
宿主 :
兔
应用 :
免疫印迹, 免疫组化-P
应用w/稀释 :
WB: 1:1, 000-1:2, 000;免疫组化-P:1:50-1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human SOD2 aa 10-50.
抗体亚型 :
IgG
靶蛋白 :
SOD2
靶标.UniProt数据库 :
P04179
靶标.同义词 :
Indophenoloxidase B antibody; IPO B antibody; IPOB antibody; Manganese containing superoxide dismutase antibody; Manganese SOD antibody; Manganese superoxide dismutase antibody; Mangano superoxide dismutase antibody; Mn SOD antibody; Mn superoxide dismutase antibody; MNSOD antibody; MVCD6 antibody; SOD 2 antibody; SOD2 antibody; SODM_HUMAN antibody; Superoxide dismutase [Mn] mitochondrial antibody; Superoxide dismutase [Mn], mitochondrial antibody; Superoxide dismutase 2 mitochondrial antibody
Target function/background :
The superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anion. The SOD-2 precursor is a 222 amino acid protein that is encoded by nuclear chromatin, synthesized in the cytosol and imported posttranslationally into the mitochondrial matrix. Unlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle. Polymorphisms in the SOD-2 gene have also been implicated in nonfamilial, idiopathic, dilated cardiomyopathy in humans.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
25 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!