产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
CD3D重组兔单克隆抗体[JJ08-97](ET1701-57)
目录 :
ET1701-57
规格 :
单克隆
价格 :
JJ08-97
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JJ08-97
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1701-57
产品名称 :
CD3D重组兔单克隆抗体[JJ08-97](ET1701-57)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JJ08-97
宿主 :
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, 免疫沉淀, FC
应用w/稀释 :
WB: 1:1, 000-1:2, 000;ICC:1:100-1:500;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类
免疫原 :
Recombinant protein within human CD3D aa 106-171.
抗体亚型 :
IgG
靶蛋白 :
CD3D
靶标.UniProt数据库 :
P04234
靶标.同义词 :
CD3 antigen delta subunit antibody; CD3 delta antibody; CD3d antibody; CD3d antigen delta polypeptide (TiT3 complex) antibody; CD3d molecule delta (CD3-TCR complex) antibody; CD3D_HUMAN antibody; IMD19 antibody; OKT3 delta chain antibody; T cell receptor T3 delta chain antibody; T-cell receptor T3 delta chain antibody; T-cell surface glycoprotein CD3 delta chain antibody; T3D antibody
Target function/background :
The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers: a heterodimer of gamma and epsilon chains (γε), a heterodimer of delta and epsilon chains (δε) and a homodimer of two zeta chains (ΩΩ) or a heterodimer of zeta and eta chains (Ωh). The Ω and h chains are encoded by the same gene but differ in their carboxyl-terminal ends due to an alternative splicing event. The γ, ε and δ chains each contain a single copy of a conserved immunoreceptor tyrosine-based activation motif (ITAM). In contrast, the Ω chain contains three consecutive copies of the same motif. Phosphorylated ITAMs act as docking sites for protein kinases such as ZAP-70 and Syk and are also capable of regulating their kinase activity. The crystal structure of the ZAP-70 SH2 domains bound to the Ω chain ITAMs has been solved.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
19 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!