产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
LC3B重组兔单克隆抗体[JJ090-6](ET1701-65)
目录 :
ET1701-65
规格 :
单克隆
价格 :
JJ090-6
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JJ090-6
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫沉淀
更多信息或购买 :
HUABIO 产品网页
文章摘录数: 1
参考文献
Wang W, Yang X, Chen Q, Guo M, Liu S, Liu J, et al. Sinomenine attenuates septic-associated lung injury through the Nrf2-Keap1 and autophagy. J Pharm Pharmacol. 2020;72:259-270 pubmed 出版商
产品信息
Catalog# :
ET1701-65
产品名称 :
LC3B重组兔单克隆抗体[JJ090-6](ET1701-65)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JJ090-6
宿主 :
兔
应用 :
免疫印迹, 免疫沉淀
应用w/稀释 :
WB: 1:1, 000-1:2, 000
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human LC3 B aa 1-20 and aa 80-120.
抗体亚型 :
IgG
靶蛋白 :
LC3B
靶标.UniProt数据库 :
Q9GZQ8
靶标.同义词 :
ATG8F antibody; Autophagy-related protein LC3 B antibody; Autophagy-related ubiquitin-like modifier LC3 B antibody; LC3B antibody; LC3II antibody; MAP1 light chain 3 like protein 2 antibody; MAP1 light chain 3-like protein 2 antibody; MAP1A/1BLC3 antibody; MAP1A/MAP1B LC3 B antibody; MAP1A/MAP1B light chain 3 B antibody; MAP1ALC3 antibody; MAP1LC3B a antibody; Map1lc3b antibody; Microtubule associated protein 1 light chain 3 beta antibody; Microtubule-associated protein 1 light chain 3 beta antibody; Microtubule-associated proteins 1A/1B light chain 3B antibody; MLP3B_HUMAN antibody
Target function/background :
Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP-light chain 3 beta (MAP-LC3β) and MAP-light chain 3 alpha (MAP-LC3α) are subunits of both MAP1A and MAP1B. MAP-LC3β, a homolog of Apg8p, is essential for autophagy and associated to the autophagosome membranes after processing. Two forms of LC3β, the cytosolic LC3-I and the membrane-bound LC3-II, are produced post-translationally. LC3-I is formed by the removal of the C-terminal 22 amino acids from newly synthesized LC3β, followed by the conversion of a fraction of LC3-I into LC3-II. LC3 enhances fibronectin mRNA translation in ductus arteriosus cells through association with 60S ribosomes and binding to an AU-rich element in the 3′ untranslated region of fibronectin mRNA. This facilitates sorting of fibronectin mRNA onto rough endoplasmic reticulum and translation. MAP LC3β may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
14/16 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
HUABIO 产品网页
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!